Over the past several years our research has focused on the development of classical regression models that describe the disposition process occurring in an electro-spouted bed system. Previous analyses addressed the development of linear regression models that related the chemical plating process to electric current levels, liquid flow rates and bed geometry, i.e. intrinsic engineering paramet...

Motivated by the three-dimensional serpentine channel (Liu et al. in J Microelectromech Syst 9:190–197, 2000), we introduce a chaotic serpentine mixer (CSM) and demonstrate a systematic way of utilizing a mapping method to find out an optimal set of design variables for the CSM. One periodic unit of the mixer has been designed to create two streamlines portraits crossing each other. As a prelim...

In this work we present a numerical study of a mixing process used for the heating of highly viscous fluids. The two rod rotating mixer in question generates chaotic flow streams by means of temporal modulations of velocity. Mixing and heating performances are shown to be dependant on the direction of rotation, as well as other geometrical and physical parameters. We also reveal the self-simila...

Lipid nanoparticles (LNPs) or liposomes are the most widely used drug carriers for nanomedicines. The size of LNPs is one of the essential factors affecting drug delivery efficiency and therapeutic efficiency. Here, we demonstrated the effect of lipid concentration and mixing performance on the LNP size using microfluidic devices with the aim of understanding the LNP formation mechanism and con...

In order to fully explore and utilize the advantages of droplet-based microfluidics, fast, sensitive, and quantitative measurements are indispensable for the diagnosis of biochemical reactions in microdroplets. Here, we report an optical detection technique using two-photon fluorescence lifetime imaging microscopy, with an aligning-summing and non-fitting division method, to depict two-dimensio...

1. Wiggins S, Ottino JM (2004) Foundations of chaotic mixing. Philos Trans Royal Soc London Series A – Math Phys Eng Sci 362(1818):937–970 2. Ottino JM (1997) The kinematics of mixing: stretching, chaos and transport. Cambridge University Press, Cambridge 3. Aref H (1984) Stirring by Chaotic Advection. J Fluid Mech 143(Jun):1–21 4. Bottausci F, Mezic I, Meinhart CD, Cardonne C (2004) Mixing in ...

The aim of this work is to introduce a novel statistical technique for quantifying the concentration field uniformity liquid-liquid mixing process within micro-scale chaotic pipeline. For illustration, microscale mixer in which inlet direction parallel unit designed by using pipeline with Baker map. Meanwhile, non-uniformity coefficient method adopted quantificationally instead qualitatively es...

This paper explores the effect of impeller design on the chaotic mixing in a helical ribbon mixer. Numerical simulations using the Smoothed Particle Hydrodynamics (SPH) method are used to solve for the fluid flow around the moving impellor. The mixing flow is visualised by extracting the hyperbolic Lagrangian Coherent Structures (LCS) of the flow from the Finite-Time Lyapunov Exponent (FTLE) fi...