PURPOSE Previous studies have shown that adenosine agonists are effective in reducing intraocular pressure (IOP). However, the mechanism(s) responsible for this ocular hypotensive effect has not been established. This study evaluates the relative contribution of changes in aqueous flow and outflow facility associated with the ocular hypotensive response to the adenosine agonist cyclohexyladenos...

The effect of charge hydration asymmetry (CHA)-non-invariance of solvation free energy upon solute charge inversion-is missing from the standard linear response continuum electrostatics. The proposed charge hydration asymmetric-generalized Born (CHA-GB) approximation introduces this effect into the popular generalized Born (GB) model. The CHA is added to the GB equation via an analytical correc...

Rita Maciel, Raquel Palma, Pedro Sousa, Fátima Ferreira, Hipólito Nzwalo Department of Internal Medicine, Centro Hospitalar do Algarve (CHA), Faro, Portugal Stroke Unit, Centro Hospitalar do Algarve (CHA), Faro, Portugal Department of Neurology, Centro Hospitalar do Algarve (CHA), Faro, Portugal Department of Cardiology, Centro Hospitalar do Algarve (CHA), Faro, Portugal Department of Biomedica...

introduction: the role of adenosine a1 receptors of the entorhinal cortex on amygdaloid kindled seizures was investigated. material and methods: animals were kindled by daily electrical stimulation of amygdala. in the full kindled animals, n6-cyclohexyladenosine (cha; 0.1, 1 and 10 mm), an adenosine a1 receptor agonist, and 8-cyclopenthyle 1,3-dimethylexanthine (cpt), an adenosine a1 receptor a...

The aim of the study was to analyze the relation between motor abilities and performance in folk dances originating from the island of Hvar and modern social dances. Two groups of variables were used in a sample of 78 female students of the Teacher Training College from Split: 7 motor variables as a battery of predictors, and performance evaluation of 4 dances (2 folk dances, i.e. ciciliona and...

Carbonated hydroxyapatite (CHA) bone cement is capable of self-setting and forming structures similar to mineralized bone. Conventional CHA leaves little room for new bone formation and delays remodeling. The purposes of this study were to develop porous CHA (PCHA) bone cement and to investigate its physicochemical properties, biocompatibility, biodegradation, and in vivo bone repair potential....

Introduction The exclusive use of a cochlear implant (CI) in one ear allows patients to effectively hear speech in a quiet environment. However, in environments with competing noise, the processing of multiple sounds becomes complex. In an attempt to promote binaural hearing in a noninvasive manner, the use of a hearing aid in the nonimplanted ear is suggested for patients with a unilateral CI....

Although search over World Wide Web pages has recently received much academic and commercial attention, surprisingly little research has been done on how to search the web pages within large, diverse intranets. Intranets contain the information associated with the internal workings of an organization. A standard search engine retrieves web pages that fall within a widely diverse range of inform...

Continuous oral administration of sodium cyclamate(CHS-Na) to guinea pig caused the gradual increase of urinary excretion of cyclohexylamine(CHA) after a certain period. The amount of CHA excreted was not only different in individuals, but also dependent on each experiment. It was diminished when CHS-Na was administered orally with antibiotics or intraperitoneally. It was shown from the incubat...