BACKGROUND Analysis the maternal and fetal risk predictors in pregnancy in conjunction with chronic glomerulonephritis (CGN) patients are helpful to understand the influence of kidney diseases on pregnancy and the effects of pregnancy on kidney diseases. The aim of this study was to determine the predictors of adverse maternal and fetal outcomes in CGN patients. MATERIAL AND METHODS Maternal an...

Within the framework of the Dutch-Flemish programme STEVIN, the JASMIN-CGN (Jongeren, Anderstaligen en Senioren in Mens-machine Interactie Corpus Gesproken Nederlands) project was carried out, which was aimed at collecting speech of children, non-natives and elderly people. The JASMIN-CGN project is an extension of the Spoken Dutch Corpus (CGN) along three dimensions. First, by collecting a cor...

Abstract The dependency-based annotation format employed within the Spoken Dutch Corpus (CGN) project (van der Wouden et al., 2002) has been designed in such a way as to enable a transparent mapping to the derivational structures of current ‘lexicalized’ grammar formalisms. Through such translations, the CGN tree bank can be used to train and evaluate computational grammars within these framewo...

INTRODUCTION We describe a female patient with extreme reactive thrombocytosis (RT) in anti-neutrophil cytoplasmic autoantibodies (ANCA)-associated crescentic glomerulonephritis (CGN) with immune complex deposits, which has never been reported before. CASE PRESENTATION A female adolescent with symptoms of oliguria and gross hematuresis had serious renal function impairment (crescent formation...

Reactive oxygen species (ROS) act as signaling molecules that regulate nervous system physiology. ROS have been related to neural differentiation, neuritogenesis, and programmed cell death. Nevertheless, little is known about the mechanisms involved in the regulation of ROS during neuronal development. In this study, we evaluated the mechanisms by which ROS are regulated during neuronal develop...

Programmed cell death plays a critical role during cerebellar development. In particular, it has been shown in vivo and in vitro that developing cerebellar granule neurons (CGN) die apoptotically. Apoptosis involves a series of morphological changes and the activation of caspases. Inhibitor of apoptosis proteins (IAPs) is implicated in negative regulation of caspase activation and apoptotic cel...

The marine toxin gambierol, a polyether ladder toxin derived from the marine dinoflagellate Gambierdiscus toxicus, was evaluated for interaction with voltage-gated sodium channels (VGSCs) in cerebellar granule neuron (CGN) cultures. At concentrations ranging from 10 nM to 10 microM, gambierol alone had no effect on the intracellular Ca2+ concentration [Ca2+]i of exposed CGN cultures. Furthermor...

BACKGROUND Crescentic glomerulonephritis (CGN) presents a rapidly progressive glomerulonephritis clinically, in which macrophages play a crucial role in the pathogenesis. However, the precise molecular mechanism of macrophage recruitment and activation has not been fully elucidated. C-C chemokines, monocyte chemoattractant protein-1 (MCP-1) and macrophage inflammatory protein-1alpha and beta (M...

Global IPv6 deployment was slower than originally expected. As IPv4 address exhaustion approaches, IPv4 to IPv6 transition issues become more critical and less tractable. Host-based transition mechanisms used in dual-stack environments cannot meet all transition requirements. Most end users are not sufficiently expert to configure or maintain host-based transition mechanisms. CarrierGrade NAT (...

Dear Editor, Pauci-immune crescentic glomerulonephritis (Pauciimmune CGN) is the most common cause of CGN. Thrombotic microangiopathy (TMA) defi nes a clinicopathological syndrome consisting of intraluminal platelet thrombosis in the microvasculature and the presence of fragmented red blood cells and thrombocytopaenia in the peripheral blood, and may be seen in haemolytic uraemic syndrome (HUS)...