Cervical spinal cord injury (cSCI) can cause devastating neurological deficits, including impairment or loss of upper limb and hand function. A majority of the spinal cord injuries in humans occur at the cervical levels. Therefore, developing cervical injury models and developing relevant and sensitive behavioral tests is of great importance. Here we describe the use of a newly developed foreli...

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BACKGROUND Prompted by an increase in interventional pain treatments performed at the level of the cervical spine, we investigated the characteristics and patterns of injury in malpractice claims collected from January 1, 2005 to December 31, 2008. METHODS We compared claims arising from cervical pain treatments with all other chronic pain claims collected from the American Society of Anesthe...

The cervical spinal cord is at a great risk for injury during traumatic accidents occurring within people of relatively young age. Spinal cord injury can not be easily characterized clinically nor through in vitro testing. An understanding of cervical spinal cord deformation is important for defining an injury threshold of the spinal cord. Therefore, an analytical method may be beneficial for d...

BACKGROUND Individuals with cervical spinal cord injury usually sustain impairments to the trunk and upper and lower limbs, resulting in compromised sitting balance. The objectives of this study were to: 1) compare postural control of individuals with cervical spinal cord injury and able-bodied individuals; and 2) investigate the effects of foot support and trunk fluctuations on postural contro...

cortical spreading depression (csd) has been suggested to underlie some neurological disorders such as migraine. despite the intensity with which many investigators have studied sd in the brain, only a few studies have aimed to identify sd in the spinal cord. here we described the main characteristic features of sd in the spinal cord induced by different methods including various spinal cord in...

BACKGROUND Injury to the spine and spinal cord is one of the common cause of disability and death. Several factors affect the outcome; but which are these factors (alone and in combination), are determining the outcomes are still unknown. The aim of the study was to evaluate the factors influencing the outcome following acute cervical spine injury. MATERIALS AND METHODS A prospective observat...

BACKGROUND Traumatic spinal cord injury (SCI) leads to disruption of axons and macroscopic tissue loss. Using diffusion tensor imaging (DTI), we assessed degeneration of the corticospinal tract (CST) in the cervical cord above a traumatic lesion and explored its relationship with cervical atrophy, remote axonal changes within the cranial CST and upper limb function. METHODS Nine cervical inju...

Impaired respiratory function is a common and devastating consequence of cervical spinal cord injury. Accordingly, the development safe effective treatments to restore breathing critical. Acute intermittent hypoxia has emerged as promising therapeutic strategy treat insufficiency in individuals with Since original report by Bach Mitchell (1996) concerning long-term facilitation phrenic motor ou...

We describe the case of a trauma patient who presented to our emergency department with signs and symptoms suggestive of cervical cord injury. The patient had an underlying ossification of the posterior longitudinal ligament with multiple cervical disc prolapses from C3 to C7. The presence of these two factors increased the impact of the traumatic cervical cord injury. The patient underwent spi...