Journal:
:iranian journal of basic medical sciences
0
asghar abdoli department of virology, faculty of medical sciences, tarbiat modares university, tehran, iran
hoorieh soleimanjahi department of virology, faculty of medical sciences, tarbiat modares university, tehran, iran
fatemeh fotouhi influenza research lab, department of virology, pasteur institute of iran, tehran, iran
shahram pour beiranvand department of anatomy, faculty of medical sciences, tarbiat modares university, tehran, iran
zahra kianmehr influenza research lab, department of virology, pasteur institute of iran, tehran, iran
objective(s): infection by high-risk papillomavirus is regarded as the major risk factor in the development of cervical cancer. recombinant dna technology allows expression of the l1 major capsid protein of hpv in different expression systems, which has intrinsic capacity to self-assemble into viral-like particles (vlp). vlps are non-infectious, highly immunogenic and can elicit neutralizing a...