OBJECTIVES Stage 1 palliation of hypoplastic left heart syndrome requires the interruption of whole-body perfusion. Delayed reflow in the cerebral circulation secondary to prolonged elevation in vascular resistance occurs in neonates after deep hypothermic circulatory arrest. We examined relative changes in cerebral and somatic oxygenation with near-infrared spectroscopy while using a modified ...

BACKGROUND It is well established that aging and vascular processes interact to disrupt cerebral hemodynamics in older adults. However, the independent effects of cerebral perfusion on neurocognitive function among older adults remain poorly understood. We examined the associations among cerebral perfusion, cognitive function, and brain structure in older adults with varying degrees of vascular...

Cerebral hyperperfusion syndrome is a rare but serious complication of carotid revascularization, and characterized by ipsilateral headache, hypertension, seizures, focal neurological deficits. Therefore, treatment strategies are directed towards regulation blood pressure limitation rises in cerebral perfusion to prevent edema or hemorrhage, especially during several days after endarterctomy st...

This comprehensive review summarizes the evidence regarding use of cerebral autoregulation-directed therapy at the bedside and provides an evaluation of its impact on optimizing cerebral perfusion and associated functional outcomes. Multiple studies in adults and several in children have shown the feasibility of individualizing mean arterial blood pressure and cerebral perfusion pressure goals ...

PURPOSE Selective cerebral perfusion with the open proximal technique for thoracoabdominal aortic repair has not been conclusively validated because of its procedural complexity and unreliability. We report the clinical outcomes, particularly the cerebroneurological complications, of an open proximal procedure using selective cerebral perfusion. METHODS A retrospective chart review identified...

Transcranial perfusion monitoring provides early warning of impending brain ischemia and may be used to guide management of cerebral perfusion and oxygenation. The monitoring options include measurement of intracranial and cerebral perfusion pressures, assessment of cerebral blood flow, and assessment of the adequacy of perfusion by measurement of cerebral oxygenation and brain tissue biochemis...

Early diagnosis of acute cerebral infarction is critical due to the time limit of thrombolytic treatment. Cerebral computed tomography (CT) perfusion imaging is a new technique, which appears to provide early diagnosis of major vessel occlusions in the brain. CT perfusion imaging also provides valuable information about the hemodynamic status of ischemic brain tissue. In this report, we present...