OBJECT Although it is generally acknowledged that a sufficient cerebral perfusion pressure (CPP) is necessary for treatment of severe head injury, the optimum CPP is still a subject of debate. The purpose of this study was to investigate the effect of various levels of blood pressure and, thereby, CPP on posttraumatic contusion volume. METHODS The left hemispheres of 60 rats were subjected to...

Maung Thaik, of Padu village, Sagaing District, was brought to the Sagaing Civil Hospital in an unconscious state with the left half of his body paralysed at 2-15 p.m. on the 8th April, 1922. A contused wound was present on the left side of the head, said to have been received ill an assault committed with a stick, at about 2 a.m. on the same day, while he was under the influence of liquor. The...

Neurogenic stunned myocardium (NSM) is a well-known complication of subarachnoidal hemorrhage, but has been reported rarely in association with other central nervous system disorders. A case of NSM is described in a patient with hemorrhagic brain contusion associated with cerebral edema. An 18-year-old man was admitted with severe cranial trauma following a car roll-over. Six days after admissi...

A previously healthy 6-week-old boy was accidentally dropped on his head on a linoleum floor. He cried immediately, with no loss of consciousness, vomiting, seizure, or obvious neurologic abnormality , and fell asleep spontaneously within 10 min after the accident without his normal feeding . Physical examination by the pediatrician about 30 min later was normal except for a hematoma in the rig...

The magnitude of damage to cerebral tissues following head trauma is determined by the primary injury, caused by the kinetic energy delivered at the time of impact, plus numerous secondary injury responses that almost inevitably worsen the primary injury. When head trauma results in a cerebral contusion, the hemorrhagic lesion often progresses during the first several hours after impact, either...

A case is reported in which several days afiter a relautvely minor closed head injury progressive, fatal neurological deterioration set in. Necropsy showed spreading oortical uhrombophlebitis originating from a small area of cerebral contusion. Some cases of progressive focal cerebral oedema and necrosis occurring after head injury mnight have a similar pathological basi's, and if this were so ...