Rapid vascular resistance adjustments in the brain and in the circle of Willis have been continuously measured and enhanced by signal averaging methods. Naftidrofuryl, a drug chemically similar to local anesthetics and to beta adrenergic blocking agents, increases local CBF by reducing resistance in brain and in extracerebral supply arteries. It has also been reported to affect brain metabolism...

CEREBRAL BLOOD FLOW Edited by M. Brock, C. Fieschi, D. H. Ingvar, N. A. Lassen, and K. Schurmann. (Pp. xx + 291; 113 figures; DM 58). Springer: Berlin. 1970. Measurement of the cerebral blood flow using isotope techniques is a field in which European centres have held the lead since their introduction by Lassen and Ingvar and by Harper exactly 10 years ago. Conferences at which the initiated ar...

V0 is the vascular distribution volume for the tracer in the tissue. In bolus type experiments such as H2O PET, this term is significant, whereas for inhalation of Xenon, the vascular term is not generally included, and Vo = 0. To measure CBF, the free parameters in Eq 1 are varied to obtain an optimal fit of the expression to regional uptake curves, using non-linear, least squared regression a...

The results of studies utilizing the nitrous oxide technic for measuring cerebral blood flow have been reviewed and divided into three groups: (1) those in which cerebral blood flow and metabolism were normal, (2) those in which cerebral blood flow was increased, and (3) those in which cerebral blood flow and metabolism were decreased. The factors which apparently regulate and control cerebral ...

BACKGROUND The use of Intra-aortic counterpulsation is a well established supportive therapy for patients in cardiac failure or after cardiac surgery. Blood pressure variations induced by counterpulsation are transmitted to the cerebral arteries, challenging cerebral autoregulatory mechanisms in order to maintain a stable cerebral blood flow. This study aims to assess the effects on cerebral au...