Central giant cell granuloma (CGCG) is an uncommon, benign, proliferative, and nonodontogenic lesion whose etiology is not defined. Thought to represent a reparative response to intrabony haemorrhage and inflammation, CGCG was once regarded as a reactive lesion. Central giant cell granuloma usually is an asymptomatic lesion, which may become evident during routine radiographic examination or as...

Introduction: Central giant-cell is a benign lesion that predominantly involves the bone of the mandible and maxilla with a wide variation of its behavior. Surgery usually is the first choice in treatment of central giant cell granuloma. Case Report: In this case report we present a 29 years-old female with well define swelling on left maxilla. Diagnosis through incisional biopsy showed a centr...

Central giant cell granuloma is a benign, aggressive neoplasm composed of multinucleated giant cells that almost exclusively occurs in the jaws though extra- gnathic incidence is rare. Multifocal CGCGs of the jaws are very rare and suggestive of systemic diseases such as hyperparathyroidism, an inherited syndrome such as Noonan- like multiple giant cell lesion syndrome or other disorders.Very f...

Central giant cell Granuloma is a intraosseous benign lesion. It occurs mostly in first three decades of life and commonly occurs in females. The lesions grew slowly and usually presented clinically as painless swellings. Radiographically they appeared as well-defined unilocular or multilocular radiolucencies with undulating borders. This case is a rare occurrence of Central Giant Cell Granulom...

INTRODUCTION Oral peripheral and central giant cell granulomas are lesions with little-known etiology and pathogenesis. OBJECTIVE The aim of this study was to compare matrix metalloproteinases-2 and osteopontin protein expression in the multinucleated giant cells and mononuclear cells of the peripheral and central giant cell granuloma lesions. METHODS In this retrospective study, the presen...

objective: oral lesions are among the important reasons for seeking dental care. being frequently encountered, giant cell lesions form an important group of oral lesions. the epidemiologic data on these lesions, however, is scarce in iran. the present study investigated epidemiological and demographic characteristics of giant cell lesions in oral biopsies done in one of the largest oral patholo...

Fibrous dysplasia (FD) is a developmental tumor like condition that is characterized by replacement of normal bone by an excessive proliferation of cellular fibrous connective tissue intermixed with irregular bony trabeculae. Central giant cell granuloma (CGCG) is described as a benign lesion affecting the mandible and maxilla that consists of a massive fibrohistiocytic proliferation with numer...

Giant cell granuloma is rare in the head and neck region and most commonly affects the maxilla and mandible. Giant cell granulomas are benign but occasionally aggressive lesions that are traditionally treated with surgery. Because it is a benign process, less radical and non-surgical treatment alternatives are required. Corticosteroid injection is a viable alternative in the treatment of centra...

The glycogen storage disease (GSD) is a group of inherited disorders that involve deficiencies in the enzymes that metabolize glycogen. The purpose of the present paper is to report a rare case of GSD type 1b that presented both peripheral and central giant cell granuloma, and to discuss the possible explanation for this unusual finding. The use of corticosteroids in the management of central g...