Five flavonoid glycosides were isolated from the n-butanol soluble fraction of the ethanolic extract of Rapistrum rugosum and their structures were assigned from 1H- and 13C-NMR spectra (DEPT) with 2D NMR as quercetin-3-O-α-L-rhamnopyranoside (1), quercetin-3-O-β-D-xyloside (2), quercetin, 3-O-α-L-arabinopyranoside,7-O-α-L-rhamnopyranoside (3), kaempferol 3-O-α-L-arabinopyranoside, 7-O-α-L-rham...

Introduction: Stereotactic body radiotherapy delivers hypofractionated irradiation with high dose per fraction through complex treatment techniques. The increased complexity leads to longer dose delivery times for each fraction. The purpose of this study is to investigate the impact of prolonged fraction delivery time with high-dose hypofractionation on the killing of cultured ACHN cells.Method...

Background: Evaluation of cell viability is momentous in pharmacologic and oncological research. Cell viability evaluation determines cell sensitivity and consequently treatment outcome. Various methods are available to determine cell survival. Each of these methods evaluates different endpoints. Accordingly, determining the correlation between these methods is important. In this study, in orde...

Flavonoids are potentially immunomodulatory factors and it may be inferred that these phytochemicals contribute to immunomodulatory properties of the Allium family. In the present study, we investigated the potential mechanism underlying the immunomodulatory effect of shallot and its ethyl acetate (EA) fraction as flavonoid-rich sources. Ex vivo, effects of a hydroalcoholic extract of shallot, ...

five flavonoid glycosides were isolated from the n-butanol soluble fraction of the ethanolic extract of rapistrum rugosum and their structures were assigned from 1h- and 13c-nmr spectra (dept) with 2d nmr as quercetin-3-o-α-l-rhamnopyranoside (1), quercetin-3-o-β-d-xyloside (2), quercetin, 3-o-α-l-arabinopyranoside,7-o-α-l-rhamnopyranoside (3), kaempferol 3-o-α-l-arabinopyranoside, 7-o-α-l-rham...

flavonoids are potentially immunomodulatory factors and it may be inferred that these phytochemicals contribute to immunomodulatory properties of the allium family. in the present study, we investigated the potential mechanism underlying the immunomodulatory effect of shallot and its ethyl acetate (ea) fraction as flavonoid-rich sources. ex vivo, effects of a hydroalcoholic extract of shallot, ...

background: for adult all patients, the indications and appropriate timing of allogeneic hematopoietic stem cell transplantation (ahsct) continue to be debated. the primary aim of this single-institution study was to compare the results of our adult all patients that had been allografted with those reported in the current literature. subjects and methods: this study included 53 consecutive adul...

objective(s): glioblastoma multiforme (gbm) is one of the most lethal forms of human cancer and temozolomide (tmz) is currently part of the standard treatment for this disease. combination therapy using natural substances can enhance the anti-cancer activity of tmz. the purpose of this study was to evaluate the effect of tmz in combination with thymoquinone (tq) on human gbm cell line (u87mg). ...

purpose: to report the clinical findings and compare the outcomes of different surgical techniques evolved over time in a large series of patients with delayed-onset mustard gas keratitis (mgk). methods: this interventional retrospective case series includes patients with complications of delayed mgk. medical and surgical interventions to address dry eye, limbal ischemia and limbal stem cell de...

background: astronauts will be exposed to both chronic space radiation and acute high doses of energetic radiation of solar particle events in long-term deep space missions. the application of radioprotectors in space missions has basic limitations such as their very short time window as well as their acute toxicity and considerable side effects. the aim of the present study was to investigate ...