Bacteriostatic and bactericidal antibiotic treatments result in two fundamentally different phenotypic outcomes--the inhibition of bacterial growth or, alternatively, cell death. Most antibiotics inhibit processes that are major consumers of cellular energy output, suggesting that antibiotic treatment may have important downstream consequences on bacterial metabolism. We hypothesized that the s...

Abstract Mitochondria evolved through an ancient endosymbiotic process and are essential for eukaryotic cellular metabolism. An emerging body of literature indicates that some cells export mitochondria delivery to other cells, a termed intercellular transfer. Recently, we demonstrated adipocytes transfer macrophages in vivo this maintains white brown adipose tissue homeostasis (Brestoff et al.,...

results the mean age in breathing technique with lavender and breathing technique alone were 25.5 ± 4.3 and 26 ± 4.9, respectively .two groups were comparable in this regards (p = 0.6), but the length of active phase in interventional group was 7.85 ± 3.85 hours and in the control group it was 9.88 ± 6.65 hours. the decrease of the length of labor in the active phase was higher in the experimen...

A L T H O U G H there is considerable evidence that carbohydrate metabolism plays an important part in the process of cell division (see Bullough, 1952), conclusions have differed regarding the relative importance of glycolysis and catabolism involving respiration. In the adult mouse epidermis Bullough & Johnson (1951) found that cell division was dependent upon the respiratory oxidation of pyr...

BACKGROUND/AIMS Deleterious effects of saturated fatty acids in skeletal muscle cells are well known but their impact on mitochondrial respiration has not been well studied. Mitochondrial oxidative damage has been implicated to play a role in their effect. The purpose of this study was to evaluate viability, mtDNA integrity and mitochondrial respiration in C2C12 myoblasts and myotubes exposed t...

THE HISTORY OF CELL REsPIRATION AND CYTOCHROME. By David Keilin. Cambridge, Cambridge University Press, 1966. xix, 416 pp. $17.50. It is a rare and happy occasion when a man who was the father of a field of knowledge, now burgeoned into a vast and complicated literature, can lead us gently and logically along its paths of growth. In 1925 David Keilin, then known as a parasitologist, published a...

Mitochondrial respiration is important for cell proliferation; however, the specific metabolic requirements fulfilled by respiration to support proliferation have not been defined. Here, we show that a major role of respiration in proliferating cells is to provide electron acceptors for aspartate synthesis. This finding is consistent with the observation that cells lacking a functional respirat...

Soil respiration (Rs) is a major pathway by which fixed carbon in the biosphere is returned to the atmosphere, yet there are limits to our ability to predict respiration rates using environmental drivers at the global scale. While temperature, moisture, carbon supply, and other site characteristics are known to regulate soil respiration rates at plot scales within certain biomes, quantitative f...