Abstract Comparative single-cell studies of group 3/4 medulloblastomas (MBs) and fetal brain have identified a common hierarchy glutamatergic-lineage cell types an apparent cell-of-origin in the rhombic lip. An increased understanding genetic regulators stem-cell maintenance differentiation MB would clearly be therapeutic benefit. There is significant need for lineage-tracing systems to model m...

lineage in the islamic law is one of the most basic human rights each individual inherits from his family. when modern assisted reproductive technologies appeared in recent decades, the issue of lineage and the child’s rights did not encounter serious challenges. but with the advent of these technologies, the issue of the child’s lineage resulting from new technologies has become the center of ...

background: mesenchymal stem cells (msc) are a very promising transplantable stem cell source for a variety of cell replacement therapies. as the main source of msc is bone marrow (bm), most of studies have been done on bm-derived msc (bm-msc). umbilical cord (uc)-derived msc (uc-msc) which are recently introduced, is one of the good alternative source for these cells. the objective of this stu...

Introduction: Introduction: Molecular components within the microenvironment act upon cell growth, survival/apoptosis, and proliferation. Immune system cells respond to molecules produced by the tumor and released in the surrounding microenvironment, such as cytokines, chemokines, and growth factors. This study aimed to identify the effects of tumor environment on monocyte-macrophage cell linea...

all-trans retinoic acid (atra), as an active metabolite of vitamin a, has been shown to affect immune cells. this study was performed to evaluate the effect of atra on viability, proliferation, activation and lineage-specific transcription factors of cd4+ t cells. cd4+ t cells were  separated  from  heparinized  blood  of  healthy  donors  and  were  cultured  in conditions, some with, some wit...

undoubtedly, the legislator has paid special attention toward protection of lineage of persons so as the weakest evidence like lottery may be used to establish a lineage under the shiite jurisprudence. therefore, the value and credit of scientific evidence such as dna test in proving lineage is very clearly acceptable. but the point worth considering here is evaluating whether such scientific e...