It has been reported that different species of Euphorbia (Euphorbiaceae) have antitumor activity. Some reports also show that these plants have potential cytotoxic effect against different cell lines. In a program to screen the cytotoxicity of Iranian native plants, Euphorbia macroclada Boiss. was collected, identified, and the cytotoxic activity of dichloromethane, ethy...

background and objectives: alzheimer's disease (ad) as a neurodegenerative disorder is the most common form of dementia in the elderly. according to the amyloid hypothesis, accumulation of amyloid beta (aβ) plaques, which are mostly constituted of aβ peptide aggregates, triggers pathological cascades that lead to neuronal cell death. thus, modulation of aβ toxicity is the hopeful therapeut...

background: many natural products from plants have been recognized to exert anticancer activity. in this study, ethanolic extracts of selected medicinal herbs from iranian flora including alyssum homolocarpum fisch. (from seeds), urtica dioica l. (from aerial parts), cichorium intybus l. (from roots) and solanum nigrum l. (from fruits), were evaluated for their cytotoxic effect on different cel...

several attempts have so far been made in the search of new anticancer agents of plant origin. some studies have reported that different species of pine genus possess cytotoxic activities against various cancer cell lines. in the present study, we evaluated the cytotoxic effects of pinus eldarica bark and leaf extracts or leaf essential oil on hela and mcf-7 tumor cell lines. hydroalcoholic and...

Isolation of some potent anti-tumor compounds from medicinal plants has motivated researchers to screen different parts of plant for their anti-tumor effects. It has been reported that several species of conifers posses’ cytotoxic activities on some tumor cell lines. Here branchlets and berries of Juniperus foetidissima and J. sabina were collected, dried and ethanol extracts of them obtain...

Isolation of some potent anti-tumor compounds from medicinal plants has motivated researchers to screen different parts of plant for their anti-tumor effects. It has been reported that several species of conifers posses’ cytotoxic activities on some tumor cell lines. Here branchlets and berries of Juniperus foetidissima and J. sabina were collected, dried and ethanol extracts of them obtain...

background: urtica dioica is one of the medicinal herbs with many uses in treating various diseases. in some studies, its antiproliferative and apoptotic effects on cancer cell lines have been shown. therefore, the evaluation of u. dioica effect was performed on kg-1 cell line for acute myelogenous leukemia (aml) for the first time in this study. materials and methods: kg-1 cell line was treate...

Background: Numerous molecules in Papaveraceae family display interesting cytotoxic activities against tumor cell lines in vitro and hints of anticancer activities in vivo have been reported in a few cases. Objective: Numerous molecules in this family display interesting cytotoxic activities against tumor cell lines in vitro and hints of anticancer activities in vivo have been reported in a fe...

abstract the antineoplastic activities of alcoholic and aqueous extracts of the roots, stems and leaves of isatis campylocarpa an endemic species of the brassicaceae family from iran, investigated on the growth of jurkat as an acute lymphocytic leukemia cell line, k562 as a chronic myelogenous leukemia cell line and fen as a bladder cancer cell line using colorimetric assay. results showed that...