نتایج جستجو برای: cell cycle
تعداد نتایج: 1862685 فیلتر نتایج به سال:
background and aims: the latency-associated transcript (lat) transcribed by latent herpes simplex virus type-1 in neuron cells are able to influence their host cell pathways. while the most of previous studies were focused on anti-apoptotic effects of lat, our investigation is making an effort to explore lat potency on cell cycle pathway in neuroblastoma cell lines. methods: the evaluation of l...
Background and Aims: The latency-associated transcript (LAT) transcribed by latent Herpes Simplex Virus type-1 in neuron cells are able to influence their host cell pathways. While the most of previous studies were focused on anti-apoptotic effects of LAT, our investigation is making an effort to explore LAT potency on cell cycle pathway in neuroblastoma cell lines. Methods: The evaluation of L...
چکیده ندارد.
Cancer is characterized by abnormally excessive cell proliferation. Cell proliferation, the process by which a cell grows and divides to produce two daughter cells. Each of these daughter cells divides to produce two new cells, steps that are called cell cycle. Meanwhile, apoptosis is a highly regulated process of cell death, which is involved not only in the development of shape and morphogene...
objective(s):eukaryotic translation initiation factor 4e (eif4e) is overexpressed in cervical cancer (cc). however, the molecular mechanisms are unclear. this study aimed to investigate the molecular mechanism of eif4e gene overexpression in cc. materials andmethods:the human papillomavirus (hpv) type 18 e7 and eif4e mrnas were measured following knock down or overexpression of e7 gene by rt-pc...
Accumulation of gene changes and chromosomal instability in response to cellular DNA damage lead to cancer. DNA damage induces cell cycle checkpoints pathways. Checkpoints regulate DNA replication and cell cycle progression, chromatin restructuring, and apoptosis. Checkpoint kinase 2 (chk2) is activated in response to DNA lesions. ATM phosphorylate chk2. The activated Chk2 kinase can phosphoryl...
Exergy analysis of an integrated molten carbonate fuel cell-turbo expander-steam turbine hybrid cycle has been presented in this study. The proposed cycle has been used as a sustainable energy approach to provide a micro hybrid power plant with high exergy efficiency. To generate electricity by the mentioned system, an externally reformed molten carbonate fuel cell located upstream of the combi...
Background & Aim: Chlorine has been known as a mucus membranes and respiratory tract irritant. This gas can increase free radicals which cause cell damage. The aim of the present study was to measure DNA content and cell cycle in white blood cells after chronic chlorine poisoning. Materials & Methods: A clinical experimental study was carried out on 80 male mice(40 mice as sample and 40 as ...
cytokines influence cell cycle events, which in some but not all instances can be associated with melanoma progression. analysis of the g0/g 1 and s phase fractions of the cell cycle was used to assay the proliferative or inhibitory activity of cytokines against ten human melanoma cell lines, including pairs of cell lines derived from primary and metastatic tissue of individual patients. cytoki...
The objective of this study was to evaluate the apoptotic effects of increasing granulosa cell density and increasing estradiol on relative gene expression associated with apoptosis factors (Bcl-2, Bax and GADD45β) and cell cycle (CCDN-2). For this reason after collecting ovaries of cows from an abattoir, granulosa cells were separated from 4- to 8-mm follicles. Then, viable cells were counted ...
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