نتایج جستجو برای: cd105

تعداد نتایج: 1193  

Journal: :Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie 2015
Dan Silviu Goldiş Mircea Florin Sferdian Cristian Tarţă Lazăr Octavian Fulger Bogdan Dan Totolici Carmen Neamţu

Endothelial cells are highlighted using a variety of endothelial markers. One of the best known markers is CD34, a surface antigen. The most used immunohistochemical marker for identification of activated endothelial cells is CD105. We chose to compare these two markers in order to evaluate angiogenesis of the rectal cancers by determining the microvessel density (MVD). Our study included 31 pa...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2009
Yu-Quan Xiong Hui-Chuan Sun Wei Zhang Xiao-Dong Zhu Peng-Yuan Zhuang Ju-Bo Zhang Lu Wang Wei-Zhong Wu Lun-Xiu Qin Zhao-You Tang

PURPOSE Increasing evidence indicates that tumor-derived endothelial cells (TEC) possess a distinct and unique phenotype compared with endothelial cells (NEC) from adjacent normal tissue and may be able to acquire resistance to drugs. The aim of this study was to investigate the angiogenesis activity and response to drug treatment of TECs and NECs derived from human hepatocellular carcinoma (HC...

2012
Suk Jae Kim Gyeong Joon Moon Yeon Hee Cho Ho Young Kang Na Kyum Hyung Donghee Kim Ji Hyun Lee Ji Yoon Nam Oh Young Bang

Preclinical and clinical studies have shown that the application of CD105(+) mesenchymal stem cells (MSCs) is feasible and may lead to recovery after stroke. In addition, circulating microparticles are reportedly functional in various disease conditions. We tested the levels of circulating CD105(+) microparticles in patients with acute ischemic stroke. The expression of CD105 (a surface marker ...

Journal: :Tumori 2009
Toshitsugu Nakamura

UNLABELLED AIMS AND BACKGROUND; Hepatic tissues, including bile canaliculi and sinusoids, around primary or metastatic tumors are destructed and regenerate associated with tumor growth, and may show some phenotypic changes. The present study was undertaken to examine the expression of CD10 in bile canaliculi [CD10(BC)] and CD105 (endoglin) along hepatic sinusoids [CD105(HS)] in peritumoral hepa...

Journal: :American journal of clinical pathology 2013
Zaher I Chakhachiro Zhuang Zuo Tariq N Aladily Hagop M Kantarjian Jorge E Cortes Khaled Alayed Martin H Nguyen L Jeffrey Medeiros Carlos Bueso-Ramos

OBJECTIVES To assess CD105 (endoglin) expression in 119 acute myeloid leukemia (AML) and 13 control cases using immunohistochemistry. METHODS CD105 expression was assessed retrospectively by using immunohistochemistry in bone marrow specimens. RESULTS CD105 was strongly and diffusely positive in all 9 (100%) AMLs with t(15;17)(q24.1;q21.2), 2 (100%) AMLs with t(8;21)(q22;q22), 1 (100%) AML ...

Journal: :The Journal of Cell Biology 2005
Petra Muenzner Manfred Rohde Susanne Kneitz Christof R. Hauck

Exfoliation, which is the detachment of infected epithelial cells, is an innate defense mechanism to prevent bacterial colonization. Indeed, infection with Neisseria gonorrhoeae induced epithelial detachment from an extracellular matrix (ECM) substrate in vitro. Surprisingly, variants of N. gonorrhoeae that bind to human carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) failed ...

Journal: :Archives of otolaryngology--head & neck surgery 2011
Gino Marioni Alberto Staffieri Enzo Manzato Giovanni Ralli Marco Lionello Luciano Giacomelli Vlatko Prosenikliev Rosario Marchese-Ragona Alessandra Busnardo Francesco Bolzetta Stella Blandamura

OBJECTIVES To ascertain the prognostic role of endoglin (CD105)-assessed microvessel density (MVD) in patients older than 65 years with laryngeal squamous cell carcinoma (LSCC), and whether this MVD differed in the elderly patients from younger adult controls. DESIGN Retrospective clinicopathologic investigation. SETTING Academic tertiary referral center. PATIENTS Fifty-seven consecutive ...

Journal: :FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000
C Li I N Hampson L Hampson P Kumar C Bernabeu S Kumar

CD105 (endoglin), a receptor for transforming growth factor beta (TGFbeta), is highly expressed in tissue-cultured, activated endothelial cells in vitro and in tissues undergoing angiogenesis in vivo. The absence of CD105 in knockout mice leads to their death from defective vascular development, but the role of CD105 in the modulation of angiogenesis has not been elucidated. TGFbeta1 is a well-...

Journal: :JAMA otolaryngology-- head & neck surgery 2013
Fang Hou Yuemeng Dai James R Dornhoffer James Y Suen Chun-Yang Fan Ali G Saad Lisa M Buckmiller Gresham T Richter

IMPORTANCE Endoglin (CD105) and endothelial nitric oxide synthase (eNOS) assist in regulating vascular development. Variation in expression of these factors is linked to errors in vascular growth and remodeling in invasive lesions. OBJECTIVE To clarify the role of endoglin and eNOS in the growth of extracranial head and neck arteriovenous malformations (AVMs), an invasive and high-flow vascul...

Journal: :Journal of Angiogenesis Research 2009
Ana Luque Mark Slevin Marta M Turu Oriol Juan-Babot Lina Badimon Jerzy Krupinski

BACKGROUND Previous studies have demonstrated that expression of CD105 is a sensitive marker and indicator of endothelial cell/microvessel activation and proliferation in aggressive solid tumour growth and atherosclerotic plaque lesions. Since intimal neovascularization contributes significantly to subsequent plaque instability, haemorrhage and rupture. METHODS We have used immunohistochemica...

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