Fe deficiency may increase Cd accumulation in peanuts. However, the mechanisms are not yet fully understood. In the present study, two contrasting peanut cultivars, Luhua 8 (low seed-Cd cultivar) and Zhenghong 3 (high seed-Cd cultivar) were used to investigate the effect of Fe deficiency on the uptake and accumulation of cadmium (Cd) by hydroponic experiments. Under Fe-sufficient conditions, co...

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The CD2 glycoprotein has been implicated in both positive ment of positive selection, the lack of CD2 was associated and negative regulation of T-cell mitogenesis. To study the with defects in proliferative responses and interferon-g proinvolvement of CD2 in T-lymphocyte development and imduction when transgenic thymocytes and mature T lymphomune responses, we have analyzed two lines of CD2-nul...

Antibody-mediated CD4 crosslinking results in increased tyrosine phosphorylation and tyrosine kinase activity of the associated p56" . Treatment with anti-CD4 and anti-Ig also induced the phosphorylation of p56kk in a CD45mutant cell line, indicating that the increase in phosphotyrosine content of p56kk is not the result of being sequestered from CD45 protein tyrosine phosphatase (PTPase) . Ant...

We present four patients with adult T-cell leukemia (ATL) derived from a novel T-cell subset (CD4-, CD8[doublenegative, DN], T-cell receptor [TCR] &). In the ATL cells of these patients, neither gene nor surface expression of CD4 and CD8 antigens was detected. Clinical and laboratory data showed no difference between DN-ATL and CD4+ATL patients. In contrast to typical CD4+ATL cells, DN-ATL cell...

BACKGROUND A number of studies have shown that the chronic stress of caring for persons with dementia can have significant immunological consequences as demonstrated by the down-regulation/dysregulation of the cellular immune response. METHODS Utilizing flow cytometry to measure the percentages and absolute numbers of CD-4(+) and CD-8(+) T lymphocytes producing the cytokines indicative of Th-...

Although both the CD4 and CD8 molecules enhance antigen responsiveness mediated by the T cell receptor (TCR), it is not known whether CD4 and CD8 initiate similar or different intraceUular signals when they act as coreceptors. To characterize the early signals transmitted by CD4 and CDS, both CD4 and CDSo~ were expressed in the same murine T cell hybridoma. In the double positive transfectants,...