نتایج جستجو برای: cd 117 antigen

تعداد نتایج: 260768  

Journal: :Blood 1989
P von den Driesch R Bhardwaj H D Flad D C Neugebauer H J Pielken D Urbanitz E Kölsch

An immunoglobulin M (IgM)-positive cell line, Ms 28, apparently spontaneously transformed by Epstein-Barr virus (EBV) was established from peripheral blood cells of a patient with immature myeloblastic leukemia. It has been characterized according to phenotype, cytochemistry, and membrane antigen pattern. The cell line expresses lymphoid markers like CD 19, CD 22, and CD 30 and synthesizes and ...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2010
Alena A Chekmasova Thapi D Rao Yan Nikhamin Kay J Park Douglas A Levine David R Spriggs Renier J Brentjens

PURPOSE Most patients diagnosed with ovarian cancer will ultimately die from their disease. For this reason, novel approaches to the treatment of this malignancy are needed. Adoptive transfer of a patient's own T cells, genetically modified ex vivo through the introduction of a gene encoding a chimeric antigen receptor (CAR) targeted to a tumor-associated antigen, is a novel approach to the tre...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1988
H Sadeghi A M da Silva C Klein

We describe the biochemical features of the putative cell cohesion molecule antigen 117, indicating that it is anchored to the plasma membrane by a glycolipid tail. Antigen 117 can be radiolabeled with [3H]myristate, [3H]palmitate, and [14C]ethanolamine. The fatty acid label is removed by periodate oxidation and nitrous acid deamination, indicating that the fatty acid is attached to the protein...

Journal: :Blood 2005
Adrian Woolfson Justin Stebbing Brian D M Tom Kerryn J Stoner Walter R Gilks David P Kreil Stephen P Mulligan Larissa Belov Jeremy S Chrisp Will Errington Adrian Wildfire Wendy N Erber Mark Bower Brian Gazzard Richard I Christopherson Mike A Scott

Cluster of differentiation (CD) antigens are expressed on cells of myeloid and lymphoid lineages. As most disease processes involve immune system activation or suppression, these antigens offer unique opportunities for monitoring host responses. Immunophenotyping using limited numbers of CD antigens enables differentiation states of immune system cells to be determined. Extended phenotyping inv...

Journal: :Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 2010
Merih Tepeoğlu Gonca Özgün M Zeyneb Tunca Tugan Tezcaner B Handan Özdemir

OBJECTIVE The clinical behavior of gastrointestinal stromal tumors is divergent. The aim of the present study was to define the clinicopathological features that determine the patient's outcome. MATERIAL AND METHOD Sixty-five gastrointestinal stromal tumors were reviewed with their histological, immunohistochemical and clinical features and compared with their clinical outcome statistically. ...

Ali Rezaie, Mohammad Abdollahi, Mohammad Hossein Yazdi, Mohammad Rostami-Nejad, Shekoufeh Nikfar,

Crohn's disease (CD) is an inflammatory disease of the gastrointestinal tract (GIT) tract and can affect several parts of the digestive system. There is a relationship between impaired mucosal barrier in the GIT of inflammatory bowel disease patients and the role of bacteria such as Mycobacterium avium paratuberculosis in CD. Apart from different therapeutic approaches for treating CD, developm...

Background: Crohn's disease and Ulcerative colitis are known as inflammatory bowel disease with high morbidity which are as a result of increasing immune responses to intestinal microbiota in genetically susceptible individuals. The association of adherent invasive Escherichia coli with Crohn's disease in human has been discussed for decades. The principal aim of this study was to assess the re...

Journal: :Hippokratia 2014
I Tsitouridis Ch Maskalidis St Pervana E Pazarli E P Kariki

AIM To describe a case of primary granulocytic sarcoma. CASE DESCRIPTION A 43-year-old man presented with a painless testicular swelling. There was no previous history of malignancy or hematologic disease. Ultrasound and magnetic resonance imaging examination showed an intratesticular mass extending to the surrounding scrotal tissues including the epididymis. Inguinal radical orchiectomy was ...

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