"Cochlea wave propagation...” These words started off David Kemp's seminal 1978 contribution to auditory biophysics, where he first described "a new auditory phenomenon” [JASA 64(5): 1386-1391]. The impact of this report has transcended numerous disciplines, finding an impressive range of scientific and clinical applications (e.g., monitoring cochlear status to ototoxicity, biophysical models o...

The cannabinoid CB(1) (CB(1)) and dopamine D(2) (D(2)) receptors are coexpressed in the basal ganglia, an area of the brain involved in such processes as cognition, motor function, and emotional control. Several lines of evidence suggest that CB(1) and D(2) receptors may oligomerize, providing a unique pharmacology in vitro and in vivo. However, limited information exists on the regulation of C...

BACKGROUND The chronic bronchitis (CB) phenotype has been associated with poor quality of life and an increased risk of disease in patients with COPD. However, little information exists regarding the relationship between the CB phenotype and the COPD assessment test (CAT) score. The goal of this study was to reveal the different pattern of CAT scores between CB and non-CB patients. Moreover, we...

The essential oil obtained from the aerial part of Chenopodium botrys plant by steam distillation was obtained. remaining aqueous extracted with solvent ethylacetate and n-butanol, respectively. In end, five extracts were obtained: (CB-EO), untreated extract (CB-F), (CB-EA), n-butanol (CB-nBu) processed (CB-L). effects on both insecticidal (against Sitophilus granarius Tribolium castaneum) enzy...

This study assessed the incidence of cytomegalovirus (CMV) infection after transplantation of cord blood (CB) from unrelated donors and evaluated strategies for screening CB donors. Posttransplantation CMV infection, reported in 23% of 1221 CB recipients, was associated with patient pretransplantation CMV serology (P < .001), but not with CMV serology in CB donors or their mothers. A total of 2...

carrie bradshaw: When a girl gets backed up against a wall she can’t afford, she has to consider renting others (sniffing through open window). Do . . . Do I smell curry? realtor: There’s an Indian restaurant downstairs. cb: Delia, I ask you, how can this apartment be $2,800 a month? I pay $750 for something that’s twice the size and it don’t smell like takeout. realtor: You have a rent-control...

Umbilical cord blood (CB) offers an alternative source of hematopoietic stem cells (HSCs) to treat patients with malignant and non malignant hematologic diseases, such as leukemia, lymphoma, myeloma, Fanconi anemia, myelodysplasia and sickle cell anemia [1]. Umbilical CB contains a low cell dose, and the first transplantation CB was performed in children with Fanconi anemia, by Gluckman and col...

Neural stem cells (NSCs) are self-renewing cells that can differentiate into multiple neural lineages and repopulate regions of the brain after injury. We have investigated the role of endocannabinoids (eCBs), endogenous cues that modulate neuronal functions including neurogenesis, and their receptors CB(1) and CB(2) in mouse NSCs. Real-time PCR and Western blot analyses indicated that CB(1) is...