The aim of the present research was to study the effects of weak cation exchange resins, polacrilex with exchangeable H+ and polacrillin potassium and strong cation exchange resin sodium polystyrene sulfonate on water uptake behavior of ranitidine hydrochloride. Drug resin complexes (DRC) were prepared and evaluated for the percentage of moisture gain when placed in a humidity c...

Reports describing trials of exchange resins in removing cations from the gastrointestinal tract of experimental animals have been limited to toxicity studies and to measurements of the relative magnitudes of the oral intake and the stool output (1-3). In the experiments presented in this paper changes in serum, urine, and stool components, as well as the external and internal balances of certa...

• PK216LH, which is a cation-exchange resin, could remove NH 4 + in an aqueous solution. The simultaneous use of Mg–Al LDO and PK216LH not sufficiently lactate . individual two stages efficient proliferation pluripotent stem cells mass cell culture hindered by the release metabolites such as ammonia. In this work, porous strong-acid cation exchange resin (PK216LH) layered doubled oxide (LDO) we...

An ion-exchange resin containing carboxylic acid groups was prepared by reaction of epoxidized soybean oil with triethylene tetramine, followed by hydrolysis of glycerides by using sodium hydroxide solution. The cation exchange capacity of the resins was determined to be 3.50 mequiv/g. The adsorption capacity for Cu , Ni , and Co on the obtained resin at pH 5.0 was found to be 192, 96, and 78 m...

An integrated all flow-through technology platform for the purification of therapeutic monoclonal antibodies (mAb), consisting of activated carbon and flow-through cation and anion exchange chromatography steps, can replace a conventional chromatography platform. This new platform was observed to have excellent impurity clearance at high mAb loadings with overall mAb yield exceeding 80%. Robust...