this study determines the value of linkage analysis using six rflp markers for carrier detection and prenatal diagnosis in familial dmd/bmd cases and their family members for the first time in the iranian population. we studied the dystrophin gene in 33 unrelated patients with clinical diagnosis of dmd or bmd. subsequently, we determined the rate of heterozygosity for six intragenic rflp marker...

one of the big concerns of big cities is facing with the increase of fossil fuel vehicles in the roads. the cars intensify greenhouse gas emission in civic centers. one approach to reduce the emission is replacing the cars by plug-in electric vehicles (pevs). in spite of reducing the emission, pevs have some adverse effect on electric distribution networks. technical challenges such as load and...

gene therapy as a modern therapeutic approach has not yet advanced to a globally-approved therapeutic approach. lack of adequate reliable gene delivery system seems to be one of the major reasons from the pharmaceutical biotechnology point of view. main obstacles delaying successful application of human gene therapy are presented in this review. the unique advantages of non-biological gene carr...

silicon nanowire (sinw) arrays were produced by electroless method on polycrystalline si substrate, in hf/ agno3 solution. although the monocrystalline silicon wafer is commonly utilized as a perfect substrate, polycrystalline silicon as a low cost substrate was used in this work for photovoltaic applications. in order to study the influence of etching time (which affects the sinws length) on d...

this study was undertaken in order to ascertain the carrier rate of group a hemolytic streptococci in the throats of pupils in selected schools of tehran, and to evaluate the role of socio-economical factors on carrier state. during the period of six months, 7020 children and adolescents, aged 10 to 17, were studied. these pupils were visited at their schools and their socio-economical level wa...

hepatitis b virus (hbv) is a crucial public health problem with approximately 350 million affected people and a death rate of 0.5 to 1.2 million per year worldwide. it proceeds to end-stage liver diseases including cirrhosis with hepatic decompensation and hepatocellular carcinoma (hcc). pakistan lies in the endemic region with 3% hbv carrier rate in the country. the differences in disease outc...

conclusions similarly to other geographical regions of iran, the sccmec type iii mrsa strain was the most frequently isolated strain from patients in gorgan. staphylococcal cassette chromosome mec type iii showed fewer virulence factors compared to other sccmec types. results the most common sccmec type was type iii, with a frequency rate of 76%, followed by types iv, i, and v, with frequency r...

objective(s): researchers have intended to reformulate drugs so that they may be more safely used in human body. polymer science and nanotechnology have great roles in this field. the aim of this paper is to introduce an efficient drug delivery vehicle which can perform both targeted and controlled antibiotic release using magnetic nanoparticles grafted ph-responsive polymer.  methods: fe3o4 na...

a study was carried out to determine whether naturally-occurring weeds and other cultivated plants in tomato growing regions could act as symptomless reservoirs of infection to fusarium oxysporum f. sp. lycopersici. a numher of f. oxysporum isolates from weeds and oubergines were used in this investigation. a susceptible tomato cultivar was used for comparison. the plants were artificially ...

background and objectives : in iran, anaplasmosis is normally diagnosed with traditional giemsa staining method. this is not applicable for identification of the carrier animals. the aim of this study was to compare the detection of anaplasma marginale in two different numbers of microscopic fields (50 and 100) using conventional giemsa staining method compared with the pcr-rflp technique. mate...