objective(s):paclitaxel is a potent chemotherapy agent with severe side effects, including allergic reactions, cardiovascular problems, complete hair loss, joint and muscle pain, which may limit its use and lower its efficiency. the cardioprotective effect of royal jelly was investigated on paclitaxel-induced damages. materials and methods:adult male wistar rats were divided into control and te...

Two cardiovascular outcome trials established niacin 3 g daily prevents hard cardiac events. However, as detailed in part I of this series, an extended-release (ER) alternative at only 2 g nightly demonstrated no comparable benefits in two outcome trials, implying the alternative is not equivalent to the established cardioprotective regimen. Since statins leave a significant treatment gap, this...

objective: the study was conducted to evaluate cardioprotective effect of silk cocoon (abresham) bombyx mori (b. mori) on isoprenaline-induced myocardial infarction. this study deals with the cocoons, which is called abresham in the unani system of medicine. it is one of the 64 drugs which avicenna has mentioned in avicenna’s tract on cardiac drugs and used in the treatment of cardiovascular di...

OBJECTIVE Heart failure (HF) is one of the most serious diseases worldwide. S-propargyl-cysteine (SPRC), a novel modulator of endogenous hydrogen sulfide, is proved to be able to protect against acute myocardial ischemia. In order to produce more stable and sustainable hydrogen sulfide, we used controlled release formulation of SPRC (CR-SPRC) to elucidate possible cardioprotective effects on HF...

Objective(s): To study the effect of acute and repeated stress on cardioprotection-induced by remote ischemic preconditioning (RIPC).Materials and Methods: RIPC was induced by giving 4 short cycles of ischemia and reperfusion, each consisting of five min. The Langendorff’s apparatus was used to perfuse the isolated rat hearts by subjecti...