objective(s): menopause and diabetes obviously increase the risk of cardiovascular disease in women. the aims of the present study were to evaluate the effects of ovariectomy in type 2 diabetes on the histology and expression of mirna-29, mirna-133, igf-1 and bcl-2 genes and bcl-2 protein and caspase 3 activity in the hearts of female rats. materials and methods: forty female wistar rats were d...

abstract background: aprotinin has been used increasingly to reduce postoperative blood loss in open-heart operations due to the potentialities for complications and high cost, it would seem reasonable to use aprotinin more selectively in small doses in the prime solution of the pump. methods: we prospectively studied the effect of preoperative low dose aprotinin [2 million units (230mg)] on bl...

the most frequent congenital heart defects in the neonatal period are ventricular septal defects. ventricular septal aneurysms can rarely develop from an interventricular septal (ivs) defect in adults. we describe a 47-year-old man with an aneurysm in the ivs growing towards the right ventricle, which was confirmed by cardiac computed tomographic angiography and was missed by echocardiography.

from march 1990 to may 1993,309 patients underwent redo cardiac surgery operation at the shahid rajai heart hospital in tehran. early mortality rates in these patients showed a significant increase in comparison to patients undergoing open heart surgery for the first time. late mortality (at least one month after surgery) in the patients was slightly increased also but less than early mortality...

a 67-year-old male suffering from depressive symptomatology was admitted to the inpatient clinic at firat university school of medicine; and his psychiatric evaluation revealed major depressive episode according to dsm-iv. he developed chest discomfort, chest pain and shortness of breath of acute onset accompanying pulseless ventricular tachycardia (vt) leading to cardiac arrest following sertr...

a role of adenosine in pathogenesis of syndrome x has recently been postulated. previous studies suggest that aminophylline (an adenosine receptor blocker) improves exercise tolerance in this disorder. present study was performed to examine the efficacy of theophylline in syndrome x and to determine the incidence of cardiovascular risk factors and clinical, ecg and angiographic findings in thes...

introduction a sudden loss of consciousness followed by abnormal movements can be ictal or syncopal in origin. transient response by the brain to sudden decrease of blood flow may cause sudden loss of consciousness followed by abnormal movements that mimic seizure. dysrhythmia is one of the important and critical reasons of such events that should be differentiated from seizure. case presentati...

cardiac laceration from blunt thoracic trauma is not a common presentation. the rate of mortality due to this injury is very high since it is not diagnosed and treated immediately. in this study, we present the case of a 65-year-old man with blunt cardiac trauma, causing right atrial rupture and pericardial tamponade. successful management of this patient was firstly done with initial pericardi...

in this investigation, 25 adult new zealand white rabbits randomly selected from both sexes and studied.coloured latex injection and corrosion cast methods were applied on the materials. this study was carried out to disclose the distribution of the cardiac veins of the new zealand white rabbits. the veins that drain the heart were found to be the great cardiac vein, the middle cardiac vein, th...