Cardiac function is thought to play a central role in determining thermal optima and tolerance limits in teleost fishes. Investigating proteomic responses to temperature in cardiac tissues may provide insights into mechanisms supporting the thermal plasticity of cardiac function. Here, we utilized a global proteomic analysis to investigate changes in cardiac protein abundance in response to tem...

Midthoracic spinal cord injury (SCI) is associated with enhanced cardiac sympathetic activity and reduced cardiac parasympathetic activity. The enhanced cardiac sympathetic activity is associated with sympathetic structural plasticity within the stellate ganglia, spinal cord segments T1-T4, and heart. However, changes to cardiac parasympathetic centers rostral to an experimental SCI are relativ...

Over the past two decades, several populations of cardiac stem cells have been described in the adult mammalian heart. For the most part, however, their lineage origins and in vivo functions remain largely unexplored. This Review summarizes what is known about different populations of embryonic and adult cardiac stem cells, including KIT(+), PDGFRα(+), ISL1(+)and SCA1(+)cells, side population c...

objective brain abscesses represent organized foci of suppuration within the parenchyma. here we report a 3 month-old girl with a very huge complicated cerebral abscess, and the course of treatment given. the patient's recovery was excellent. the follow up mri showed only subtle porencephalic changes as the only parenchymal sequelae, which may be due to cns plasticity in infants.

migraine is a primary headache which is very common in the society. although it is usually starts in a salient point in life span of an individual diagnostically, the repetition of acute stress response such as sleep abnormalities, anxiety, and depression are not new in this population. therefore, they have had almost a long diary of these abnormalities. in order to understand the role/s of str...

The Neuregulin is a member of the epidermal growth factors (EGF) family of receptor kinases, was originally identified as the product of the transforming gene derived from chemically induced rat neuroblastoms. A variety of different protein isoforms are produced from single Neuregulin gene. Four distinct vertebrate gene encode Neuregulin, prosaically named NRG1, NRG2, NRG3, and NRG4. Most of bi...

The molecular basis underlying the dedifferentiation of mammalian adult cardiomyocytes (ACMs) into myocyte-derived cardiac progenitor cells (mCPCs) during cardiac tissue regeneration is poorly understood. We present data integrating single-cell transcriptome and whole-genome DNA methylome analyses of mouse mCPCs to understand the epigenomic reprogramming governing their intrinsic cellular plast...

landmark based geometric morphometrics and comparison of meristic characters was used to understand potential differences between populations of waspi in mashkil and mokran basins. 97 specimens of waspies were caught (64 from mashkil river and 33 from sarbaz river). 14 landmarks were digitized on pictures taken from left side of specimens and meristic characters were counted. data were analyzed...