Objective(s): Cirrhotic cardiomyopathy refers to cardiac muscle dysfunction caused by liver cirrhosis. Seemingly, free radicals and inflammatory factors play a critical role in the pathophysiology of cardiomyopathy. Curcumin has the anti-inflammatory, antioxidant, and anticancer properties . However, the therapeutic indications of this compound are limited due to its low absorption, rapid metab...

Objective(s): This study investigated the protective effect of tanshinone IIA sodium sulfonate (TSS) on ischemia-reperfusion (I/R) induced cardiac injury, and the underlying mechanism of action. Materials and Methods:Male Sprague-Dawley rats were subjected to a 30-min coronary arterial occlusion followed by 24 hours' reperfusion. Half an hour before the left coronary artery ligation, rats were ...

Abstract Background Thalassemia intermedia is a variety of beta thalassemia which shows clinical symptoms somewhere between asymptomatic carriers and thalassemia major. Cardiac dysfunctions due to chronic anemia and hemosiderosis are the major causes of death in these patients. The purpose of this study is to evaluate cardiac function in these patients by echocardiography. Materials and Met...

objective(s): this study investigated the protective effect of tanshinone iia sodium sulfonate (tss) on ischemia-reperfusion (i/r) induced cardiac injury, and the underlying mechanism of action. materials and methods:male sprague-dawley rats were subjected to a 30-min coronary arterial occlusion followed by 24 hours' reperfusion. half an hour before the left coronary artery ligation, rats ...

Objective(s): Existing studies have demonstrated that intravenous and intramyocardial-administrated mesenchymal stem cells (MSCs) lead to tissue repair after cardiac disorders. We compared the efficiency of both administration methods.Materials and Methods: A rat model of isoproterenol-induced heart failure (ISO-HF) was established to co...

background: sickle-cell disease (scd) is an inherited hemoglobin childhood disorder, frequently complicated by pulmonary hypertension and cardiac involvement. cardiovascular events and complications are the leading cause of mortality and morbidity in patients with scd. tissue doppler imaging and the myocardial performance index (tei index), are simple indices for the assessment of the cardiac f...

conclusions children engaged with regular football practice presented enhanced physical fitness and autonomic function, by increasing vagal tone at rest. results the anthropometric and body composition characteristics were similar in both groups (p > 0.05). the groups were also similar in time spent daily on moderate-to-vigorous physical activities (fg vs. cg: 114 ± 64 vs. 87 ± 55 minutes; p > ...

Background: Cardiac dysfunction due to chronic anemia and hemosiderosis are the major causes of death among patients with thalassemia intermedia. This study was performed to compare the cardiac function in thalassemia intermedia patients with normal subjects by means of echocardiography. Materials and Methods: This was a case-control study performed on 22 patients affected by thalassemia int...