The impact of low-level carbon monoxide exposure on ventricular arrhythmia frequency in patients with ischemic heart disease has not been thoroughly studied. The issue is of concern because of the potential proarrhythmic effect of carbon monoxide in patients with ischemic heart disease. We studied 30 subjects with well-documented coronary artery disease who had an average of at least 30 ventric...

background: this toxicological investigation involves a report on the death of four ‎occupants of a sport utility vehicle on one of the major busy federal roads of nigeria ‎where they were held for up to three hours in a traffic jam while the car was steaming.‎ methods: autopsy was executed using the standard procedure and toxicological ‎analysis was done using simple spectrophotometric method ...

conclusions in patients without clear signs of myocardial infarction, even mild co poisoning was associated with quantifiable circulating levels of hs-ctnt when tnt was measured using a highly sensitive assay in the current study patients. plasma levels of the hs-tnt and ck-mb assays were not correlated with the cohb levels in the current study patients. results the mean age of the patients was...

the aim of this study was to define the electrocardiogram (ecg) changes following the moderate to severe co intoxication in rats, and also evaluating the effect of erythropoietin (epo) on observed cardiac disturbances. the growing literature on erythropoietin effect on cardiac ischemia led us to question its effect on cardiotoxicity due to the carbon monoxide poisoning. wistar rats were exposed...

AN electrochemical sensor has previously been reported to provide useful detection of carbon monoxide while exposed to one minimum alveolar concentration of volatile anesthetics. My independent laboratory study yields further evidence supporting the possible utility of electrochemical carbon monoxide sensor measurements in anesthetic gas mixtures. Several scientific investigations have elucidat...

A site for the binding of exogenously added carbon monoxide has been identified at the active site of the Fe-only hydrogenase (CpI) from Clostridium pasteurianum. The binding and inhibition of carbon monoxide have been exploited in biochemical and spectroscopic studies to gain mechanistic insights. In the present study, we have taken advantage of the ability to generate an irreversibly carbon m...

Data from recent experimental and clinical studies have indicated that lower concentrations of inhaled carbon monoxide might have beneficial antiinflammatory effects. Inhaled carbon monoxide has the potential to be a therapeutic agent for chronic obstructive pulmonary diseases (COPD). However, population-based epidemiologic studies of environmentally relevant carbon monoxide exposure have gener...

BECAUSE OF VARIATION in hemoglobin concentration in normal bloods with age and sex (1), the per cent carbon monoxide saturation of hemoglobin represents a more accurate toxicity index than the volume per cent of carbon monoxide. In 2 of the most common methods of carbon monoxide determination in blood, the gasometric method of Van Slyke (2, 3, 4) and the spectrophotometric method of Harper (5),...

PURPOSE Recent data demonstrate that the mortality rate from carbon monoxide poisoning has declined over the past 2 decades. It is not known whether this decrease in mortality is reflective of the total burden of carbon monoxide poisoning. This study sought to examine trends in other potential indicators of the incidence of carbon monoxide poisoning in the United States. BASIC PROCEDURES Publ...