Background: Cancer stem-like cells (CSCs) play a crucial role in the initiation, progression, and recurrence of cancer. Evidence indicates that the high linear energy transfer (LET) carbon ion beam is more effective against CSCs than the conventional X-ray beam. Carbon ion radiotherapy is considered as a promising cancer strategy, however, information about whether, or not, new CSCs are induced...

Radiation therapy is an integral part of the multi disciplinary therapy of lung cancer. Genetic changes and the specific tumor microenvironment favour therapy resistance of tumor cells. Clinical studies suggest that particle irradiation with carbon ions may improve the therapy response of solid tumors compared to photon radiation [1]. Occurrence of therapy resistance is related to secretion of ...

Heavy charged particles interact with matter predominantly through inelastic collisions with atomic electrons. Slower particles give more energy to the electrons in comparison with faster particles; therefore, the delivered dose increases while the particle energy decreases. The point at which the particles deposit most of their energy is called the Bragg peak. The presence of a Bragg peak make...

in this work, the removal of copper from an aqueous solution by granular activated carbon (gac) in the presence of competitor ions was studied. a batch adsorption was carried out and different parameters such as ph, contact time, initial copper concentration and competitor ions concentration were changed to determine the optimum conditions for adsorption. the optimum ph required for maximum ads...

Ameloblastic carcinomas are rare odontogenic tumors. Treatment usually consists of surgical resection and sometimes adjuvant radiation. We report the case of a 71 year-old male patient undergoing carbon ion therapy for extensive local relapse of ameloblastic carcinoma. Treatment outcome was favourable with a complete remission at 6 weeks post completion of radiotherapy while RT-treatment itself...

Carbon ion radiotherapy holds great promise for cancer therapy. Clinical data show that carbon ion radiotherapy is an effective treatment for tumors that are resistant to X-ray radiotherapy. Since 1994 in Japan, the National Institute of Radiological Sciences has been heading the development of carbon ion radiotherapy using the Heavy Ion Medical Accelerator in Chiba. The Gunma University Heavy ...