نتایج جستجو برای: capsular serogroup

تعداد نتایج: 12098  

2005
Maija Toropainen

Background: Despite of the amount of work on the meningococcal serogroup B bacteria and immunity to disease caused by them, a satisfactory vaccine for these important pathogens is still missing. Several group B meningococcal vaccines based on outer membrane protein vesicles (OMV) or complexes have been evaluated in phase II and III clinical trials. Although the antibody responses in connection ...

2011
Ana Belén Ibarz-Pavón Jenny MacLennan Nicholas J. Andrews Stephen J. Gray Rachel Urwin Stuart C. Clarke A. Mark Walker Meirion R. Evans J. Simon Kroll Keith R. Neal Dlawer Ala'Aldeen Derrick W. Crook Kathryn Cann Sarah Harrison Richard Cunningham David Baxter Edward Kaczmarski Noel D. McCarthy Keith A. Jolley J. Claire Cameron James M. Stuart Martin C. J. Maiden

BACKGROUND Herd immunity is important in the effectiveness of conjugate polysaccharide vaccines against encapsulated bacteria. A large multicenter study investigated the effect of meningococcal serogroup C conjugate vaccine introduction on the meningococcal population. METHODS Carried meningococci in individuals aged 15-19 years attending education establishments were investigated before and ...

Journal: :Journal of clinical microbiology 2010
Michael R Jacobs Ron Dagan Saralee Bajaksouzian Anne R Windau Nurith Porat

Factor 6d antiserum reacts with the new Streptococcus pneumoniae serotype 6C. Serogroup 6 isolates, consisting of 49 6A, 42 6B and 98 6C strains from the United States and Israel, serotyped in parallel by PCR and capsular swelling methods, were all identified correctly. The new factor 6d antiserum accurately identifies serotype 6C.

Journal: :Infection and immunity 2005
In Ho Park Ju Ho Youn In-Hong Choi Moon H Nahm Se Jong Kim Jeon-Soo Shin

Sepsis and meningitis caused by Neisseria meningitidis serogroup B (NMGB) are serious diseases in infants and young adults, but no effective vaccine is available. The capsular polysaccharide (PS) of NMGB has poor immunogenicity and a structural similarity to polysialic acid (PSA) on neuronal tissue that may elicit autoantibodies. Using HmenB3, a protective and nonautoreactive monoclonal antibod...

2005
Z. JAGLIC Z. KUCEROVA K. NEDBALCOVA I. PAVLIK P. ALEXA M. BARTOS

The aim of this study was to characterise and compare Pasteurella multocida isolates originating from pigs (n = 43), calves (n = 31), rabbits (n = 27), and to a lesser extent from other hosts (n = 6). A total of 107 P. multocida isolates were obtained from various locations in the Czech Republic. They were analysed by capsular PCR typing and ribotyping, and tested for the production of dermonec...

Journal: :Carbohydrate Polymers 2021

• Structural elucidation of two pneumococcal capsular polysaccharides (CPS) Comparison CPS structures and biosynthesis between serotype 28 F, 28A 16 F Correlation with supported proposed function glycosyltransferase Latex agglutination revealed the importance O Ac PO 4 in serological reaction Capsular are key virulent factors pathogenesis Streptococcus pneumoniae . The previously unknown 28F we...

Journal: :Communicable diseases intelligence quarterly report 2009
John Tapsall

In 2007 there were 281 laboratory-confirmed cases of invasive meningococcal disease analysed by the National Neisseria Network, a nationwide network of reference laboratories. The phenotypes (serogroup, serotype and serosubtype) and antibiotic susceptibility of 154 isolates of Neisseria meningitidis from invasive cases of meningococcal disease were determined and an additional 127 cases were co...

2016
Shakeel Mowlaboccus Timothy T. Perkins Helen Smith Theo Sloots Sarah Tozer Lydia-Jessica Prempeh Chin Yen Tay Fanny Peters David Speers Anthony D. Keil Charlene M. Kahler

Neisseria meningitidis is the causative agent of invasive meningococcal disease (IMD). The BEXSERO® vaccine which is used to prevent serogroup B disease is composed of four sub-capsular protein antigens supplemented with an outer membrane vesicle. Since the sub-capsular protein antigens are variably expressed and antigenically variable amongst meningococcal isolates, vaccine coverage can be est...

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