OBJECTIVES To compared the effects of risedronate (Ris) and calcitriol (Cal) on cancellous bone in rats with glucocorticoid (GC)-induced osteopenia. MATERIALS AND METHODS Thirty female Sprague-Dawley rats, 4 mo of age, were randomly divided by the stratified weight method into three groups of 10 rats each according to the following treatment schedule: 8-wk GC administration with 4-wk vehicle ...

Autogenous bone grafts are frequently in use in the field of reconstructive upper extremity surgery. Cancellous bone grafts are applied to traumatic osseous defects, nonunions, defects after the resection of benign bone tumors, arthrodesis, and osteotomy procedures. Cancellous bone grafts do not only have benefits such as rapid revascularization, but they also have mechanical advantages. Despit...

INTRODUCTION Structurally intact, cancellous bone is an attractive grafting material because it can allow a greater degree of ingrowth by host tissues than cortical bone and may also be used as structural support for other biomaterials used to deliver osteogenic agents. Gamma radiation sterilization is a commonly used technique for reducing the risk of disease transmission with allograft, but i...

Aim: The study aimed to evaluate the clinical outcomes of bone augmentation with a mixture cortico-cancellous allograft and xenograft collagen membrane in horizontal knife-edge alveolar crests.
 Material Method: Patients ridge thickness less than 4 mm by preoperative tomography were included study. Twelve patients (10 Female, 2 Male) treated Cortico-Cancellous Allograft Bovine Bone Mineral...

The purpose of the present study was to compare the effects of alendronate and alfacalcidol on cancellous and cortical bone mass and bone mechanical properties in ovariectomized rats. Twenty-six female Sprague-Dawley rats, 7 months of age, were randomized by the stratified weight method into four groups: the sham-operated control (Sham) group and the three ovariectomy (OVX) groups, namely, OVX ...

To determine the effect of estrogen receptors (ER) α and β on bones' adaptive response to loading, we subjected the right tibiae of mice lacking ERα or ERβ activity to either axial loading or to disuse. Adaptive changes in architecture were assessed by comparing differences between the right (treated) and left (control) tibiae in these genotypes as assessed by microcomputed tomography. In femal...

Introduction: Cortical thickness, interradicular space width and bone density are key factors in the use of mini-implants as anchorage. Objective: This study assessed maxillary and mandibular alveolar and basal bone density in Hounsfield units (HU). Method: Eleven files with CT images of adults were used to obtain 660 measurements of bone density: alveolar (buccal and lingual cortical) bone, ca...

This study investigated microarchitectural, mechanical, collagen and mineral properties of normal adolescent cancellous bone, and compared them with adult and aging cancellous bone, to obtain more insight into the subchondral bone adaptations during development and growth. Twenty-three human proximal tibiae were harvested and divided into 3 groups according to their ages: adolescence (9 to 17 y...

It is well documented that intermittent PGE(2) treatment increases both trabecular and cortical bone mass. However, the effects of continuous PGE(2) administration remain undocumented. The aim of the study was to investigate the effects of continuous prostaglandin E(2) (PGE(2)) on different bone sites in skeletally mature rats. Six-month-old Sprague Dawley rats were treated with PGE(2) at 1 or ...

The increase of patients with osteoporosis is a social problem. Osteoporosis decreases bone strength and increases the risk of fracture. The finding of prevention and treatment methods is an urgent issue. Since cancellous bone is metabolically more active than cortical bone, cancellous bone is used for diagnosis of osteoporosis. There are a lot of studies about stress analysis of cancellous bon...