Background. Programs of preclinical safety studies the health care products depend on regulatory status investigated products. The classification such products, in particular suppositories for rectal and vaginal use, is a critical step developing tactics their biological evaluation. Adaptation evaluation methods medical devices based combination biologically active substances, as well results u...

Following the characterization of hypoglycemic, gastric emptying inhibitory, and gastroprotective principles and the structure elucidation of calendasaponins A, B, C, and D, two new ionone glucosides (officinosides A and B), and two sesquiterpene oligoglycosides (officinosides C and D), were isolated from the flowers of Egyptian Calendula officinalis. The structures of the officinosides were el...

The chemical composition and bioactive properties of two plants (Calendula officinalis L. and Mentha cervina L.) were studied. Their nutritional value revealed a high content of carbohydrates and low fat levels, and very similar energy values. However, they presented different profiles in phenolic compounds and fatty acids; C. officinalis presented mainly glycosylated flavonols and saturated fa...

background: colorectal adenocarcinoma is one of the most prevalent and treatable malignancies of the gastrointestinal tract. recent in vitro studies have demonstrated the anticancer effect of calendula officinalis extract on a tumor cell line derived from colorectal cancers. the inhibitory effect of this extract ranges from 70- 100% and an in vitro study has demonstrated that calendula officina...

Calendula officinalis (Marigold) was characterized in respect to its chemical composition, antioxidant potential and antimicrobial activities. Five compounds were identified and quantified by LC/MS and HPLC in leaves and flowers of aqueous-methanolic extracts. Total flavonoids ranged between 44.91 and 76.44 mg QE/g dry weight in leaf and flower extracts, respectively. Rutin, quercetin-3-O-gluco...

follows that the action of BHDB in inhibiting the effect of thyroxine on the oxygen consumption of mice and its opposite action in the case of triiodothyronine (Maclagan et al. 1952) cannot have been due to changes in the total excretion rate. They must therefore reflect alterations in the activity of the circulating thyroid hormone, probably consequent upon inhibition of deiodination processes.

In this study the in vitro cytotoxic properties of ethanol extracts from the herbs, inflorescents and roots of selected Asteraceae species: Arctium lappa, Artemisia absinthium, Calendula officinalis, Centaurea cyanus, Tanacetum vulgare and Tragopogon pratensis on J-45.01 human acute T leukemia cell line was examined. All tested samples possess antileukemic properties and induce cells death via ...

in order to study the effect of water deficit stress and different nitrogen levels on flower yield, yield components and water use efficiency of calendula officinalis l., an experiment was conducted as split plot based on randomized complete block design with three replications, at research field of islamic azad university, birjand branch in 2009. in this experiment, irrigation treatments (irri...