Calciphylaxis is a vascular calcification-cutaneous necrosis syndrome, usually seen in patients with end-stage renal disease and secondary hyperparathyroidism. We report a 57-year-old polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome patient complicated with extensive skin ulcers due to calciphylaxis. He first noted a painful cutaneous ulcer ...

In contrast with uraemic calciphylaxis in end-stage renal disease, causes of and risk factors for non-uraemic calciphylaxis are relatively unknown to clinicians and have yet to become fully established. This report describes a case of non-uraemic calciphylaxis, in which the use of acenocoumarol might have been a risk factor. It is important to raise awareness about this association among clinic...

Calciphylaxis is a painful, debilitating, and premorbid condition, which presents as calcified vasculature and soft tissues. Traditional diagnosis of calciphylaxis lesions requires an invasive biopsy, which is destructive, time consuming, and often leads to exacerbation of the condition and infection. Furthermore, it is difficult to find small calcifications within a large wound bed. To address...

Fig 1. Computed tomography of pancreas showing severe pancreatitis. INTRODUCTION Although pancreatitis is not uncommon, the underlying cause is usually identified from clinical history,physical examination, laboratory investigations, and radiologic imaging. Causes include alcohol, gallstones, medications, hypertriglyceridemia, and postendoscopic retrogradecholangiopancreatography. We report the...

Calciphylaxis is an entity that manifests in patients with end-stage renal disease. Also known as calcific uraemic arteriolopathy, it is associated with calcium deposits and the appearance of necrotic lesions in the skin and blood vessels. Of unclear pathogenesis, it can present with hypercalcaemia, hyperphosphataemia and secondary hyperparathyroidism. Vascular calcification is its histological...

Introduction: Calciphylaxis is a rare and lifethreatening condition in which extensive microvascular calcification in arterioles and occlusion of vessels lead to painful non-healing ulcers with high mortality rate. Calciphylaxis is mainly associated with end stage renal disease or hyperparathyroidism, with rare cases reported in cirrhosis patient. Case Report: A 55-year-old Caucasian male with ...

BACKGROUND Calciphylaxis, also called calcific uremic arteriolopathy, is a rare and often fatal complication of end-stage renal disease and is characterized by painful skin ulceration, necrosis, medial calcification and intimal proliferation of small arteries. Studies in western countries have reported incidences ranging from 1 to 4% in chronic hemodialysis patients. Since no systematic studies...

Calciphylaxis is a serious medical condition that is typically associated with end-stage renal disease and presents as the sequelae of calcifications in arterioles with subsequent ischemia of affected tissues. Classically, calciphylaxis produces ulcerated and necrotic skin lesions. These may be biopsied to aid in confirmation of the diagnosis. Herein we report a case of a large necrotic breast ...

Calciphylaxis is a small vessel vasculopathy characterized by significant calcium deposition in the vessel walls and tissue of renal failure patients. The process leads to progressive, painful, ischemic wounding. Management is generally medical; however, superinfection requires surgical intervention. A case of calciphylaxis of the breast is presented. Calciphylaxis of the breast is atypical - t...

A 62-year-old male patient presented to the hospital with sustained fever and refractory skin ulcers. He had been under haemodialysis for 11 years and had received anticoagulation therapy via warfarin following the artificial valve replacement surgery for 4 years. From his painful skin ulcers and necrotizing skin nodules with surrounding purpura over a wide range of the inferior limb, perineum,...