development of an environmental friendly and cost-effective process for microbial degradation of caffeine to non-toxic compounds are promising to solve the problems of physiochemical extraction of caffeine in the treatment the caffeine containing agro-industrial effluents. thirteen bacterial strains, isolated from tea plantation soils in the north region of iran, were screened to show their abi...

background: caffeine increases the camp production that stimulates spermatozoa movement. caffeine is also used for induction of in vitro acrosome reaction in mammalian spermatozoa, an important step in achieving fertilization. objective: the aim of this study was to assess the effect of caffeine on sperm's motility, vitality and laboratory fertilization rates in mouse in two t6 and m16 media. m...

background: in recent years concerns have been raised about human reproductive disorders, specially the effects of environmental factors on human fertility and pregnancy outcome. therefore, the present study was designed to assess the effects of maternal caffeine consumption on ovarian follicles development in rat offspring. methods: 60 pregnant female rats were randomly divided into a control ...

background: in recent years, concerns have been raised about human reproductive disorders. caffeine consumption is increasing by the world’s population and there is a relationship between caffeine intake and adverse reproductive outcomes. the aim of this study was to evaluate the effects of caffeine on implantation sites, number of live births, birth weight, crown-rump length (crl) and abnormal...

there is a great call for using microbial bio-decaffeination approach to remove caffeinefrom caffeinated products and industrial wastes. we aimed in this study to screen strainsof yeasts which exhibit high caffeine tolerance and to investigate the bio-degradation ofcaffeine under growth conditions. sixteen yeast strains were isolated from the cultivatedtea soils collected from sites of northern...

objective: non-steroidal anti-inflammatory drugs (nsaids) are the most commonly prescribed pain control medications following periodontal surgery. this study aimed to compare the efficacy of three drug regimens namely celecoxib, celecoxib + caffeine and ibuprofen for pain relief following crown lengthening surgery.   methods: this randomized, double blind clinical trial was performed on 45 pati...

background and aim: caffeine at low doses blocks adenosine receptors. these receptors are present in all parts of the body including auditory and vestibular system. this study aimed to evaluate the effects of caffeine on cervical vestibular evoked myogenic potential (cvemp). methods: in this interventional double-blind study, 40 cases (20 females and 20 males) aged 18-25 years were randomly ass...

the effect of physiological concentrations of caffeine (purified from persian tea) on adenosine deaminase (ada) activity at physiological and pathological concentrations of adenosine (as substrate) in 50 mm tris-hcl buffer (ph 7.3) at 37°c was investigated, using uv-vis spectroscopy. ada exhibited a bi-phasic activity behavior and both phases showed positive cooperativities indicating adenosine...

caffeine, an adenosine a1, a2a, and a2b receptor antagonist, is frequently used as an adjuvant analgesic in combination with non steroidal anti-inflammatory drugs or opioids. the aim of this study was to evaluate the effects of caffeine on preventing the development of morphine tolerance and analgesia in mice. in this study, different groups of mice received morphine (30 mg/kg) + saline (10 ml/...