نتایج جستجو برای: cadmium 565
تعداد نتایج: 25928 فیلتر نتایج به سال:
Study was made on the significance of urinary cadmium concentration as an indicator of internal dose in a general environment polluted by cadmium. As an index of external dose, the mean rice cadmium concentration in each of 23 villages was employed. Morning urine samples were collected from 3,178 inhabitants of 23 cadmium-polluted villages of Kakehashi River basin in Ishikawa Prefecture and 294...
1 Coley Pharmaceutical GmbH, 40764 Langenfeld, Germany 2 Institute for Medical Microbiology, Hygiene and Immunology, D-81675 Munich, Germany 3 Department of Host Defense, Research Institute for Microbial Diseases, Suita, Osaka 565-0871, Japan 4 ERATO, Japan Science and Technology Corporation, Osaka 565-0047, Japan 5 Rheumatology and Clinical Immunology, University of Florida, Gainesville, FL 32...
Hidetoshi Hamada MD 1 *, Keisuke Uemura MD 2 , Masaki Takao MD, PhD 1 , Takashi Sakai MD, PhD 1 , Takashi Nishii MD, PhD 2 , Nobuhiko Sugano MD, PhD 2 , 1* Departments of Orthopedic Surgery, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan, [email protected] 2 Departments of Orthopedic Medical Engineering, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan
BACKGROUND Environmental exposure to cadmium causes renal dysfunction and bone damage. Cadmium contamination in food is regarded as the main environmental source of non-occupational exposure. The aim of this study was to assess the contribution of dietary cadmium exposure in environmental cadmium exposure and its health risk among adults in Shanghai, China. METHODS A cross-sectional survey ab...
BACKGROUND Cadmium is a widespread environmental pollutant with adverse effects on kidneys and bone, but with insufficiently elucidated public health consequences such as risk of end-stage renal diseases, fractures and cancer. Urinary cadmium is considered a valid biomarker of lifetime kidney accumulation from overall cadmium exposure and thus used in the assessment of cadmium-induced health ef...
In three separate sets of studies, the effects of ureteral ligation and coadministration of cadmium with cysteine or glutathione (GSH) (in either a 4:1 or 2:1 ratio of thiol to cadmium) on the renal disposition of cadmium were assessed in rats 1 h after the administration of cadmium. In all experiments, co-administration of cadmium with either cysteine or GSH caused the renal accumulation of ca...
Exposure of rats to cadmium causes a marked depletion of iron in liver and kidney. Selenium neither counteracts or intensifies the influence of cadmium on tissue iron levels. Selenium injections protect against cadmium-induced testicular damage but cause this element to accumulate in the testes at higher concentration than in animals exposed to cadmium without selenium. Selenium injection diver...
The heavy metal cadmium is a non-degradable pollutant. By screening the effects of a panel of metal ions on the phosphatase activity, we unexpectedly identified cadmium as a potent inhibitor of PPM1A and PPM1G. In contrast, low micromolar concentrations of cadmium did not inhibit PP1 or tyrosine phosphatases. Kinetic studies revealed that cadmium inhibits PPM phosphatases through the M1 metal i...
Cadmium is a worldwide environmental toxicant responsible for a range of human diseases including cancer. Cellular injury from cadmium is minimized by stress-responsive detoxification mechanisms. We explored the genetic requirements for cadmium tolerance by individually screening mutants from the fission yeast (Schizosaccharomyces pombe) haploid deletion collection for inhibited growth on agar ...
The elimination of cadmium in feces was studied in a group of 15 male workers exposed to cadmium oxide dust in a nickel-cadmium battery factory. The elimination of cadmium in feces was on the average 619 and 268 microgram/day in seven smokers and eight nonsmokers, respectively. The corresponding ranges were 97-2577 and 31-1102 microgram/day. The cadmium concentrations in blood were significantl...
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