Aim: Acute appendicitis (AA) is the most common surgical emergency in the world, and its diagnosis is mainly dependent on clinical findings. Recently, secretion of CA125 from peritoneal cells due to inflammatory stimulus has been shown. The aim of this study was to evaluate the relation between CA25 levels and AA. Materials and Methods: In this prospective trial, CA125 levels were measured. Gro...

BACKGROUND The purpose of the present study was to compare the serum levels of IL6 and CA125 in women with and without endometriosis. They were also compared in mild, moderate and severe cases. METHODS In this case-control study, CA125 and IL6 levels in 76 women with laparoscopic proven endometriosis were compared with 76 women without evidence of endometriosis. Sensitivity, specificity, posi...

UNLABELLED Serum tumor marker (STM) estimation is often used in clinical practice in monitoring response to treatment and as a predictor of treatment failure and relapse. However, there are pitfalls in interpretation, particularly in the immediate post treatment period, when a rise in titre could be observed, the phenomenon being termed as "flare". A literature search was done to examine this p...

BACKGROUND Preoperative evaluation of ovarian tumors is challenging. This study was undertaken to evaluate the performance of conventional two-dimensional (2D) ultrasound and CA125 in predicting malignant or benign nature of pelvic masses, and to investigate if three-dimensional power Doppler (3DPD) ultrasound provides any added value. Ninety-six postmenopausal and four perimenopausal women wit...

Cancer antigen 125 (CA 125) is a useful tumor marker with a threshold value of 35 U mL(-1) expressed by more than 80% of patients with non-mucinous epithelial ovarian cancer. In this work, a novel strategy for the analysis of CA 125 using the plasmon resonance scattering (PRS) properties of gold nanorods was proposed. The gold nanorod (GNR)-anti-CA 125 conjugates were prepared first. The immuno...

background: ca-125 is a glycoprotein and its origin is uncertain during pregnancy. it arises during the first trimester and return to a non-pregnancy range in late pregnancy. objective: the aim of this study was to compare ca-125 level in threatened abortion and normal pregnancy less than 20 weeks of pregnancy. materials and methods: this was a prospective case study carried out on 50 healthy p...