Polyoxometalate-bis-pyrene receptors for phenyl-C61-butyric acid methyl ester (PCBM) provide an interfacial layer (IFL) material enhancing the open circuit voltage of organic photovoltaic device about 34% under applied bias ±5 V.

Kim C. Donaghuea, Francesco Chiarellib, Daniela Trottab, Jeremy Allgrovec and Knut Dahl-Jorgensend aThe Children’s Hospital at Westmead, University of Sydney, Australia; bDepartment of Paediatrics, University of Chieti, Italy; cDepartment of Paediatric Endocrinology and Diabetes, Royal London Hospital, Whitechapel, London E1 1BB, UK; dDepartment of Pediatrics, Ullevål University Hospital, and F...

Article history: Received 6 August 2010 Received in revised form 15 November 2010 Accepted 23 November 2010 Available online 2 December 2010 JEL classification: C61 E21 O41

Article history: Received 29 July 2008 Accepted 29 August 2008 Available online 5 September 2008 JEL classification: G11 G10 C61 G19

We report preclinical proof of principle for effective treatment of B-precursor acute lymphoblastic leukemia (ALL) by targeting the spleen tyrosine kinase (SYK)-dependent antiapoptotic blast cell survival machinery with a unique nanoscale pharmaceutical composition. This nanoscale liposomal formulation (NLF) contains the pentapeptide mimic 1,4-Bis (9-O dihydroquinidinyl) phthalazine/hydroquinid...

This paper examines how robust economic, political, and demographic variables are related to water and air pollution. Employing Bayesian Averaging of Classical Estimates (BACE) for a cross section of up to 74 countries, 33 variables and 3 proxies for air and water pollution over a period from 1980 to 1995 we confirm the Environmental Kuznets Curve hypothesis, highlight the relevance of efficien...

The identification of SYK as a master regulator of apoptosis controlling the activation of the PI3-K/AKT, NFκB, and STAT3 pathways-three major anti-apoptotic signaling pathways in B-lineage leukemia/lymphoma cells-prompts the hypothesis that rationally designed inhibitors targeting SYK may overcome the resistance of malignant B-lineage lymphoid cells to apoptosis and thereby provide the foundat...

Seven pyrrolizidine alkaloids (PAs) have been isolated from Lithospermum canescens and their structures determined by spectroscopical methods. Besides the known lycopsamine, O7-acetyl-lycopsamine and O7-acetylintermedine four new PAs were found. Their structures are O7-(3-hydroxy-3-methyl-butanoyl)-O9-(+)-trachelanthoyl-heliotridine (= O7-(3-hydroxy-3-methyl-butanoyl)-rinderine = canescine), O7...