Local density approximation (LDA), several popular general gradient approximation (GGA), hybrid module based density functional theoretical methods: SVWN, BLYP, PBE, HCTH, B3LYP, PBE1PBE, B1LYP, and BHandHLYP, and some nonstandard hybrid methods are applied in geometry prediction for C60 and C70. HCTH with 3-21G basis set is found to be one of the best methods for fullerene structural predictio...

Initiator tRNAs are used exclusively for initiation of protein synthesis and not for elongation. We show that both Escherichia coli and eukaryotic initiator tRNAs have negative determinants, at the same positions, that block their activity in elongation. The primary negative determinant in E. coli initiator tRNA is the C1xA72 mismatch at the end of the acceptor stem. The primary negative determ...

Antiserum performance in a nephelometric system can be characterized by parameters derived from measuring reaction rates. The characterization process is derived from a series of dose-response curves (elicited nephelometric response vs antigen concentration) generated from various dilutions of the antiserum being tested. Antiserum titer can then be calculated by plotting the antigen concentrati...

TEM5 (tumour endothelial marker 5; also known as GPR124) is an adhesion G-protein-coupled receptor containing a cryptic RGD motif in its extracellular domain. TEM5 is expressed in endothelial cells and pericytes during angiogenesis. In the present paper, we report that thrombin mediates shedding of an N-terminal TEM5 fragment of 60 kDa (termed N60) containing the RGD motif in an open conformati...

The dipper effect for contrast discrimination provides strong evidence that the underlying neural response is accelerating at low contrasts and saturating at high contrasts. The contrast-response functions of V1 neurons do have this sigmoidal shape, but individual neurons do not generally have a dynamic range wide enough to account for the dipper effect. This paper presents a Bayesian model of ...

OBJECTIVE To examine mechanisms controlling the stapedial reflex in patients with amyotrophic sclerosis (ALS). METHODS The stapedial reflex was examined using impedance audiometry in 38 patients with sporadic ALS and in 25 age matched controls. RESULTS All patients showed normal reflex decay test results. There were no significant differences between patients with ALS and control subjects i...

Yogurts are prepared by fermenting milk with bacterial cultures consisting of a mixture of Streptococcus ssp. thermophilus and Lactobacillus delbrueckii ssp. bulgaricus. The main aim of this investigation was to develop a majority goat yogurt, with the addition of sheep milk in order to have a final product with good physicochemical quality properties and sensorial attributes. Four types of yog...

O câncer de mama é o que apresenta maiores taxas incidência, prevalência e mortalidade, dentre todas as neoplasias acometem mulheres, com exceção dos tumores pele do tipo não melanoma. Tendo como objetivo analisar a tendência da mortalidade em mulheres fora faixa etária rastreamento por (CID-10 C50), no período 2000 2019 Brasil. Apresentamos este estudo exploratório série temporal óbitos neopla...

Background and Aims: Cardiac hypertrophy is a compensatory augmentation response of the heart due to pressure overload that can lead to heart failure. Carvacrol is considered as the major compound of many plants, that possesses strong antioxidant properties. The present study aimed to evaluate effect of carvacrol on catalase activity and mRNA expression following left ventricular hypertrop...