نتایج جستجو برای: bursting

تعداد نتایج: 4535  

2016
Keisuke Fujita Mitsuhiro Iwaki Toshio Yanagida

Cell-to-cell variability plays a critical role in cellular responses and decision-making in a population, and transcriptional bursting has been broadly studied by experimental and theoretical approaches as the potential source of cell-to-cell variability. Although molecular mechanisms of transcriptional bursting have been proposed, there is little consensus. An unsolved key question is whether ...

2006
Georgi S. Medvedev

We study statistical properties of the irregular bursting arising in a class of neuronal models close to the transition from spiking to bursting. Prior to the transition to bursting, the systems in this class develop chaotic attractors, which generate irregular spiking. The chaotic spiking gives rise to irregular bursting. The duration of bursts near the transition can be very long. We describe...

Journal: :Physical review. E, Statistical, nonlinear, and soft matter physics 2001
G de Vries

A two-dimensional map exhibiting chaotic bursting behavior similar to the bursting electrical activity observed in biological neurons and endocrine cells is examined. Model parameters are changed so that the bursting behavior is destroyed. We show that bursting can be recovered in a population of such nonbursting cells when they are coupled via the mean field. The phenomenon is explained with a...

Journal: :Bulletin of mathematical biology 2011
Wondimu Teka Krasimira Tsaneva-Atanasova Richard Bertram Joël Tabak

Bursting electrical activity is ubiquitous in excitable cells such as neurons and many endocrine cells. The technique of fast/slow analysis, which takes advantage of time scale differences, is typically used to analyze the dynamics of bursting in mathematical models. Two classes of bursting oscillations that have been identified with this technique, plateau and pseudo-plateau bursting, are ofte...

Journal: :Physical review. E, Statistical, nonlinear, and soft matter physics 2010
Sajiya Jalil Igor Belykh Andrey Shilnikov

We study a pair of endogenously bursting neurons with fast nondelayed inhibitory connections. We show that fast reciprocal inhibition, known to facilitate antiphase bursting, can stably synchronize bursting neurons. This contrasts with the classical view that reciprocal inhibition has to be slow or time delayed to establish in-phase synchronization. Through stability analysis, we reveal the eme...

Journal: :Journal of neurophysiology 2006
Wim van Drongelen Henner Koch Frank P Elsen Hyong C Lee Ana Mrejeru Erin Doren Charles J Marcuccilli Mark Hereld Rick L Stevens Jan-Marino Ramirez

Most types of electrographic epileptiform activity can be characterized by isolated or repetitive bursts in brain electrical activity. This observation is our motivation to determine mechanisms that underlie bursting behavior of neuronal networks. Here we show that the persistent sodium (Na(P)) current in mouse neocortical slices is associated with cellular bursting and our data suggest that th...

2006
Wim van Drongelen Henner Koch Frank P. Elsen Hyong C. Lee Ana Mrejeru Erin Doren Charles J. Marcuccilli Mark Hereld Rick L. Stevens Jan-Marino Ramirez

Most types of electrographic epileptiform activity can be characterized by isolated or repetitive bursts in brain electrical activity. This observation is our motivation to determine mechanisms that underlie bursting behavior of neuronal networks. Here we show that the persistent sodium current (Na P) in mouse neocortical slices is associated with cellular bursting, and our data suggests that t...

2004
Martin Golubitsky Krešimir Josić LieJune Shiau L. J. Shiau

Periodic bursting in fast-slow systems can be viewed as closed paths through the unfolding parameters of degenerate singularities. Using this approach we show that bursting in coupled systems can have interesting behavior. We focus on two identical cell systems and use the Z2 symmetry present in such systems to illustrate interesting bursting phenomena. In particular, we show that Hopf/Hopf mod...

Journal: :Journal of neurophysiology 2007
Y V Bobkov B W Ache

Rhythmically bursting neurons are fundamental to neuronal network function but typically are not considered in the context of primary sensory signaling. We now report intrinsically bursting lobster primary olfactory receptor neurons that respond to odors with a phase-dependent burst of action potentials. Rhythmic odor input as might be generated by sniffing entrains the intrinsic bursting rhyth...

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