Brucellosis is a zoonotic infection with a worldwide distribution, endemic in the Mediterranean region, and is associated with high morbidity in humans [1,2]. Osteoarticular complications are the most common focal complications of Brucella spp. infection [3]. These complications commonly affect the axial skeleton, with vertebral spondylitis accounting for 35%–50% of all osteoarticular complicat...

Background: Spondylodiscitis is an infective process of the disc and two adjacent vertebrae. It quite a rare disease accounting for 2–7% all cases septic osteomyelitis. These spinal infections touch commonly single level, lumbar spine being most affected. Non-contiguous level involvement seldom reported in literature. This last group part imputable to granulomatous organisms [1,2]. Objectives: ...

The findings in 40 children (24 female, 16 male) with osteoarticular complications of brucellosis are presented. Raw milk was the main source of infection. Most patients had acute onset of fever, arthralgia, and myalgia. Arthritis was the presenting symptom in all patients, of whom two also had osteomyelitis. Arthritis was monoarticular in 28 (70%) of 40 cases with predilection for large weight...

Arctic foxes (Vulpes lagopus) are susceptible to smooth Brucella (s-Brucella) infection and may be exposed such bacteria through the consumption of infected marine mammals, as implied by finding s-Brucella antibodies in polar bears (Ursus maritimus). Svalbard have not previously been investigated for s-Brucella antibodies, but antibodies detected Iceland, Alaska (USA) Russia...

Abstract Brucella spp. are facultative intracellular bacterial pathogens that have the ability to survive and multiply in professional nonprofessional phagocytes. Successful invasion chronic persistence indicate manipulates various host cellular processes create a replication permissive niche. The essential mechanisms factors support of remain poorly understood. RNA interference (RNAi) is poten...

Multilocus enzyme electrophoresis (MLEE) of 99 Brucella isolates, including the type strains from all recognized species, revealed a very limited genetic diversity and supports the proposal of a monospecific genus. In MLEE-derived dendrograms, Brucella abortus and a marine Brucella sp. grouped into a single electrophoretic type related to Brucella neotomae and Brucella ovis. Brucella suis and B...

With the aim of developing quantitative PCR methods for the detection and differentiation of Brucella species, the genomes of Brucella ceti, Brucella inopinata, Brucella netotomae, and Brucella suis biovar 4 were sequenced and analyzed.