sulfonic acid-based precursors (sap) play an important role in tailoring mesoporous silica’s and convert them to a solid acid catalyst with a bronsted-type nature. these kinds of solid acids contribute to sustainable and green chemistry by their heterogeneous, recyclable, and high efficiency features. therefore, knowing the properties and reactivity of saps can guide us to manufacture a sulfona...

The structural evolution of small copper clusters of up to 15 atoms and the dissociative chemisorption of H2 on the minimum energy clusters are studied systematically using density functional theory. The preferred copper sites for chemisorption are identified and the transition state structures and activation barriers for clusters four to nine atoms are determined and found to be inconsistent w...

A N-methyl-2-pyrrolidonium hydrogensulfate [NMP][HSO4] bronsted acidic ionic liquid-promoted cyclocondensation-cyclization pathway has been established using one pot reaction of anilines, aldehydes and mercaptoacetic acid to give 4-thiazolidinone derivatives in good promising yields microwave irradiation. Applications for this protocol are easy workup, high yields, short times, variability func...

A series of metal ion (M = Sn2+, Fe3+, Ni2+, Co2+, Ag+, Cu2+) exchanged tungstophosphoric acid (H3PW12O40; TPA) catalysts with tunable Bronsted/Lewis acidity were synthesized and exploited for the oxidation benzyl alcohol (BzOH) to benzaldehyde (BzH) using hydrogen peroxide (H2O2) as oxidant. The structure these M-TPA composite salts was also characterized by Fourier transform infrared spectros...

Glucose is one of the primary derivative products from lignocellulosic biomass, which abundantly available. has excellent potential to be converted into valuable compounds such as ethanol, sorbitol, gluconic acid, and levulinic acid (LA). Levulinic an exceptionally promising green platform chemical. It comprises two functional groups, ketone carboxylate, acting highly reactive electrophiles for...

A family 3 beta-glucosidase (EC 3.2.1.21) from Flavobacterium meningosepticum has been cloned and overexpressed. The mechanistic action of the enzyme was probed by NMR spectroscopy and kinetic investigations, including substrate reactivity, secondary kinetic isotope effects and inhibition studies. The stereochemistry of enzymic hydrolysis was identified as occurring with the retention of an ano...

Cdc25 phosphatases are dual specificity phosphatases that dephosphorylate and activate cyclin-dependent kinases (CDKs), thereby effecting the progression from one phase of the cell cycle to the next. Despite its central role in the cell cycle, relatively little is known about the catalytic mechanism of Cdc25. In order to provide insights into the catalytic mechanism of Cdc25, we have performed ...