Benzodiazepines are widely used psychoactive drugs, and have been detected in several clinical cases of accidental exposure suicide. It was reported that benzodiazepine concentration changed post-mortem blood. However, there is no concrete evidence to reasonably explain why blood cannot be accurately determined. In this study, we showed the concentrations almost all types benzodiazepines examin...

Methcathinone, a methyl derivative of cathinone, is an illicit drug also known as ephedrone. It is a stimulant found in the "khat" plant, Catha edulis, which can easily be synthesized from pseudoephedrine. Its intoxication is difficult to diagnose and cure properly for two reasons: (i) target consumers are usually "well-educated people" aware of the risks and precautionary measures and (ii) int...

In this study, an analytical methodology was developed for the determination of psycho-active drugs in the treated effluent of the University Hospital at the Federal University of Santa Maria, RS - Brazil. Samples were collected from point A (Emergency) and point B (General effluent). The adopted methodology included a pre-concentration procedure involving the use of solid phase extraction and ...

Background: The majority of patients admitted to the hospital for elective surgery experience anxiety preoperatively which can adversely influence surgical procedure as well patient’s recovery. Reduction and fear at preoperative period in is essential preparation. Benzodiazepines are most commonly used drugs this purpose. Materials Methods: study was carried out on a series 60 consecutivepatien...