Objective: To investigate the antifungal, haemolytic and cytotoxic activity of methanol and methanol: chloroform extracts of the marine Mollusks (10 Gastropods, 5 Bivalves, 2 Cephalopods) and 1 Echinoderm. Methods: Crude methanol and methanol: chloroform extracts of the marine Mollusks (10 Gastropods, 5 Bivalves, 2 Cephalopods) and 1 Echinoderm were tested for antifungal activity using disc dif...

Amalakyadi churna is an Ayurvedic formulation, which is extensively used in traditional system of Indian medicine and by folk practitioner for treating all types of fever, and other common ailments In this study, an equal concentration of ethanolic extracts of Amalakyadi churna and its ingredients (50μg/ml of artificial sea water) were subjected to a bioscreening study to detect the cytotoxic a...

in the present work, the bioassay screening of the essential oil and various extracts of two plants including fruits of heracleum persicum desf. and rhizomes of zingiber officinale rosc. have been studied with brine shrimp test. there is only one report about cytotoxicity of h. sphondylium in literature and so h. persicum has been used as second selection. at first essentials oil and various ex...

Numerous studies have been focused on natural anticarcinogenic agents. Many antioxidants have been identified as anticarcinogens. Antimutagens have also been proposed as cancer chemopreventive agents. The use of natural products as anticancer has a long history that began with traditional medicine. The aim of this study was to evaluate cytotoxicity and antioxidant activity of twenty-three plant...

Tamarindus indica is widely used as a food and beverage and in traditional medicine. The apparent lack of dose standardization in herbal medicine necessitates the evaluation of the lethality T. indica on Artemia salina nauplii and chicken embryos via in vitro and in vivo techniques. Furthermore, hepatotoxicokinetics of the crude extract and fractions on Wister rats was also assessed. At concent...

Diarrhea is one of the most common causes for thousands of deaths every year. Therefore, identification of new source of antidiarrheal drugs becomes one of the most prominent focuses in modern research. Our aim was to investigate the antidiarrheal and cytotoxic activities of methanolic extract of Maranta arundinacea linn. (MEMA) leaves in rats and brine shrimp, respectively. Antidiarrheal effec...

Cancer is one of the most distressing, life threatening disease regarding morbidity and mortality worldwide. Many folk medicinal and ornamental plants possess chemotherapeutic and chemo preventive potential. In present study, dichloromethane extract of wood, bark and root and methanol extracts of bark and root of Sanchezia speciosa were prepared. Sanchezia speciosa, an ornamental plant was eval...

Medicinal plants constitute an important component of flora and are widely distributed in India. The pharmacological evaluation of substances from plants is an established method for the identification of lead compounds which can leads to the development of novel and safe medicinal agents. Based on the ethnopharmacological literature, several species of medicinal plants used in traditional medi...

Background:Heliotropium strigosum Willd. (Chitiphal) is a medicinally important herb that belongs to the Boraginaceae family. Traditionally, this plant was used in the medication therapy of various ailments in different populations of the world. The aim of the study is to probe the therapeutic aspects of H. strigosum described in the traditional folklore history of medicines. Methods: In the pr...

The triterpenoid clionasterol (1), a 29 carbon structure compound was isolated from the less polar extract (20% EtOAc in hexanes) of the green alga Halimeda macroloba collected at Shimoni near Mombasa, Kenya. The structure and relative stereochemistry of this compound was elucidated by spectroscopic data, mainly NMR and mass spectrometry. This metabolite was inactive against DLD-1 cells on the ...