نتایج جستجو برای: breast cancer gold nanoclusters

تعداد نتایج: 1062811  

2015
Xiao-Dong Zhang Zhentao Luo Jie Chen Shasha Song Xun Yuan Xiu Shen Hao Wang Yuanming Sun Kai Gao Lianfeng Zhang Saijun Fan David Tai Leong Meili Guo Jianping Xie

Radiotherapy is often the most straightforward first line cancer treatment for solid tumors. While it is highly effective against tumors, there is also collateral damage to healthy proximal tissues especially with high doses. The use of radiosensitizers is an effective way to boost the killing efficacy of radiotherapy against the tumor while drastically limiting the received dose and reducing t...

Journal: :Nanoscale 2015
Chuanhao Yao Shubo Tian Lingwen Liao Xinfeng Liu Nan Xia Nan Yan Zibao Gan Zhikun Wu

It is well known that the fluorescence of metal nanoclusters is strongly dependent of the protecting ligand and reports of phenylethanethiolated metal nanoclusters with distinct fluorescence are rare. Herein, a fluorescent phenylethanethiolated gold nanocluster is synthesized using an unexpected pseudo-AGR method (AGR: anti-galvanic reduction). The cluster is precisely determined to be Au24(SC2...

2012
Xiangming Meng Zhao Liu Manzhou Zhu Rongchao Jin

This work presents a controlled reduction method for the selective synthesis of different sized gold nanoclusters protected by thiolate (SR = SC2H4Ph). Starting with Au(III) salt, all the syntheses of Aun(SR)m nanoclusters with (n, m) = (20, 16), (24, 20), (39, 29), and (40, 30) necessitate experimental conditions of slow stirring and slow reduction of Au(I) intermediate species. By controlling...

Journal: :Chemical communications 2015
Wei Song Ru-Ping Liang Ying Wang Li Zhang Jian-Ding Qiu

A green method was employed for synthesizing peptide-templated nanoclusters without requiring strong reducing agents. Using synthetic peptide-gold nanoclusters as fluorescence probes, a novel assay for detecting protein kinase is developed based on phosphorylation against carboxypeptidase Y digestion.

Journal: :Chemical communications 2015
Man-Bo Li Shi-Kai Tian Zhikun Wu Rongchao Jin

A new nanocluster of atomic precision, Au44(SC2H4Ph)32, is obtained by an oxidation-decomposition-recombination (ODR) process from Au25(SC2H4Ph)18 under mild conditions with high yield (75%). Among the investigated gold nanoclusters, Au44(SC2H4Ph)32 exhibits the highest catalytic activity for the reduction of 4-nitrophenol, especially at low temperature, indicating that the catalytic properties...

2012
Daniel M. Chevrier Amares Chatt Peng Zhang

Research is turning toward nanotechnology for solutions to current limitations in biomedical imaging and analytical detection applications. New to fluorescent nanomaterials that could help advance such applications are protein-stabilized gold nanoclusters. They are potential candidates for imaging agents and sensitive fluorescence sensors because of their biocompatibility and intense photolumin...

Journal: :Dalton transactions 2012
Pablo Botella Ilida Ortega Manuel Quesada Roque F Madrigal Carlos Muniesa Antonio Fimia Eduardo Fernández Avelino Corma

Combined chemo and photothermal therapy in in vitro testing has been achieved by means of multifunctional nanoparticles formed by plasmonic gold nanoclusters with a protecting shell of porous silica that contains an antitumor drug. We propose a therapeutic nanoplatform that associates the optical activity of small gold nanoparticles aggregates with the cytotoxic activity of 20(S)-camptothecin s...

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