نتایج جستجو برای: brain white matter hyperintensities

تعداد نتایج: 816747  

Journal: :AJNR. American journal of neuroradiology 2014
M C Valdés Hernández R J Piper M E Bastin N A Royle S Muñoz Maniega B S Aribisala C Murray I J Deary J M Wardlaw

BACKGROUND AND PURPOSE White matter hyperintensities are characteristic of old age and identifiable on FLAIR and T2-weighted MR imaging. They are typically separated into periventricular or deep categories. It is unclear whether the innermost segment of periventricular white matter hyperintensities is truly abnormal or is imaging artifacts. MATERIALS AND METHODS We used FLAIR MR imaging from ...

Journal: :Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine 2009
Makoto Ochi Masako Furuyama Hideyo Satoh Akira Satoh Makiko Seto Mitsuhiro Tsujihata

The origin of patchy white matter hyperintensities commonly seen in the elderly on magnetic resonance (MR) images with long repetition time (TR) is still controversial. We describe MR findings in older patients in whom white matter hyperintensities were attenuated by compression of the cerebral hemisphere from a chronic subdural hematoma. These sequential MR findings substantiate the hypothesis...

2016
Aiqing Chen Rufus O. Akinyemi Yoshiki Hase Michael J. Firbank Michael N. Ndung’u Vincent Foster Lucy J. L. Craggs Kazuo Washida Yoko Okamoto Alan J. Thomas Tuomo M. Polvikoski Louise M. Allan Arthur E. Oakley John T. O’Brien Karen Horsburgh Masafumi Ihara Raj N. Kalaria

White matter hyperintensities as seen on brain T2-weighted magnetic resonance imaging are associated with varying degrees of cognitive dysfunction in stroke, cerebral small vessel disease and dementia. The pathophysiological mechanisms within the white matter accounting for cognitive dysfunction remain unclear. With the hypothesis that gliovascular interactions are impaired in subjects with hig...

Journal: :Stroke 2008
Tracy D Vannorsdall H A Jinnah Barry Gordon Michael Kraut David J Schretlen

BACKGROUND AND PURPOSE High normal concentrations of serum uric acid (UA) are associated with mild cognitive dysfunction and increased cerebral ischemia as indexed by white matter hyperintensity volumes. We hypothesized that individual differences in white matter hyperintensities mediate the association between UA and mild cognitive dysfunction. METHODS One hundred eighty community-dwelling a...

Journal: :Archives of neurology 2008
Beth Kuczynski Bruce Reed Dan Mungas Michael Weiner Helena C Chui William Jagust

BACKGROUND Alzheimer disease and cerebrovascular disease affect elderly persons through alterations in brain structure and metabolism that produce cognitive decline. Understanding how each disease contributes to dementia is essential from both a pathophysiologic and diagnostic perspective. OBJECTIVE To elucidate how baseline cognitive function (episodic memory and executive function) and brai...

2016
David Gaist Ellen Garde Morten Blaabjerg Helle H. Nielsen Thomas Krøigård Kamilla Østergaard Harald S. Møller Jacob Hjelmborg Camilla G. Madsen Pernille Iversen Kirsten O. Kyvik Hartwig R. Siebner Messoud Ashina

A small number of population-based studies reported an association between migraine with aura and risk of silent brain infarcts and white matter hyperintensities in females. We investigated these relations in a population-based sample of female twins. We contacted female twins ages 30-60 years identified through the population-based Danish Twin Registry. Based on questionnaire responses, twins ...

Journal: :The British journal of radiology 2010
R Perrin K Embleton V W Pentreath A Jackson

MRI has previously provided conflicting results when used to search for brain abnormalities in sufferers of chronic fatigue syndrome (CFS). Eighteen CFS patients and nine healthy volunteers each underwent MRI on two occasions, one year apart. The resulting images were examined for abnormalities in brain atrophy, deep white matter hyperintensities (WMH) and cerebral blood and cerebrospinal fluid...

Journal: :Annals of the rheumatic diseases 2005
F Sardanelli A Iozzelli B Cotticelli C Losacco M Cutolo A Sulli F Nobili G Rodriguez

OBJECTIVE To evaluate the brain status of patients with systemic sclerosis (SSc). METHODS Fourteen female patients with SSc aged 24-74, with a disease duration of 1-12 years and without other relevant systemic diseases, were enrolled. All patients and an age matched female control group (CG) of 14 clinically normal subjects, underwent brain magnetic resonance examination at 1.5 T; spin echo p...

2010
Stéphanie Debette H S Markus

OBJECTIVES To review the evidence for an association of white matter hyperintensities with risk of stroke, cognitive decline, dementia, and death. DESIGN Systematic review and meta-analysis. DATA SOURCES PubMed from 1966 to 23 November 2009. STUDY SELECTION Prospective longitudinal studies that used magnetic resonance imaging and assessed the impact of white matter hyperintensities on ris...

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