background: stroke is the third leading cause of death. hypothermia has been recognized as an effective method in reducing brain injury. in this study, we assessed the effects of granulocyte colony-stimulating factor (g-csf) as a neuroprotective agent and mild hypothermia on mortality, behavioral function, infarct volume, and brain edema in wistar rats. methods: forty male rats were used in fiv...

objective(s): some histopathological alterations take place in the ischemic regions following brain ischemia. recent studies have demonstrated some neuroprotective roles of crocin in different models of experimental cerebral ischemia. here, we investigated the probable neuroprotective effects of crocin on the brain infarction and histopathological changes after transient model of focal cerebral...

Background: Stroke is the third leading cause of death. Hypothermia has been recognized as an effective method in reducing brain injury. In this study, we assessed the effects of granulocyte colony-stimulating factor (G-CSF) as a neuroprotective agent and mild hypothermia on mortality, behavioral function, infarct volume, and brain edema in Wistar rats. Methods: Forty male rats were used in fiv...

According to some studies, the number of addicted females in reproductive ages has been increased. The present study was designed to investigate the effect of oral morphine consumption on the development of CNS and body growth in rats. For this purpose, female Sprauge-Dawley rats were divided into control and experimental groups (20 animals in each group). Maintenance dose of morphine (0/4 mg/m...

According to some studies, the number of addicted females in reproductive ages has been increased. The present study was designed to investigate the effect of oral morphine consumption on the development of CNS and body growth in rats. For this purpose, female Sprauge-Dawley rats were divided into control and experimental groups (20 animals in each group). Maintenance dose of morphine (0/4 mg/m...