Glioblastoma multiform(GBM) is the most prevalent primary brain tumor. Exosomes are extracellular vehicles for exchanging information between various cell types including cancer and normal cells. Exosomes are indicative of pathophysiological conditions of brain tumors that could be used in diagnosis and prognosis of GBM. In tumors, exosomes could carry various molecules like several miRNAs and ...

background: medulloblastoma is the most common malignant brain tumor in children. the important factors in predicting survival are the extent of disease, proliferation index of the tumor cells, histopathologic class and the age at diagnosis. the percentage of ki-67 positive cells reflects the proliferation  of the cells and is one of the critical factors which determine the growth of the tumor....

primary and secondary malignant central nervous system (cns) tumors are devastating invasive tumors able to give rise to many kinds of differentiated tumor cells. glioblastoma multiform (gbm), is the most malignant brain tumor, in which its growth and persistence depend on cancer stem cells with enhanced dna damage repair program that also induces recurrence and resists current chemo- and radio...

Introduction: The brain tumor is an abnormal growth of tissue in the brain, which is one of the most important challenges in neurology. Brain tumors have different types. Some brain tumors are benign and some brain tumors are cancerous and malignant. Glioblastoma Multiforme (GBM) is the most common and deadliest malignant brain tumor in adults. The average survival rate for peo...

abstract: gestational trophoblastic neoplasm (gtn) is among rare human tumors which can be observed with widespread metastasis. two young patients with emergent neurologic symptoms with no gynecological problems are presented in this report. gtn was later diagnosed in both cases with brain metastasis. the first case: a 22 years old patient, admitted to the infectious disease ward, with probable...

    Abstract   The Intraparenchymal schwannomas are very rare tumors with only 52 reported   cases . We describe a 38 years old man with eight months history of poorly controlled   seizures despite of medical therapy. On brain CT scan a 1.5 x 1.5 cm hypodense enhancing lesion was seen in right posterior-inferior frontal lobe. On brain MRI the lesion   was hypointense in T1 and hyperintense in T...

purpose: to report a case of unilateral severe visual loss and bilateral optic disc cupping secondary to brain metastasis of bronchogenic carcinoma patient and findings: a 48 year-old woman presented with severe visual loss of left eye without redness or pain or any systemic findings .clinical findings included decreased visual acuity of left eye to 4 m cf and (+3) positive marcus-gunn reflex ....

background : the brain is a rare site of metastases from ovarian cancer. limited data are available on prognostic factors, standard treatment, and survival. knowledge of clinical prognostic factors would help the management of patients with brain metastases. the aim of this study is to evaluate the impact of clinical factors and treatment modalities on survival in patients with brain metastases...

hydatidosis is a parasitic disease in all over the world which is caused by a cestode (tape worm). liver, lung, and brain are the most common involved organs and involvement of muscles and bones is unusual. we report a 32years old man who had low back and radicular leg pain. he had a paravertebral mass with involvement of spinal column. this patient was operated with differential diagnosis of t...