introduction: in this study the evaluation of a platelet-based maximum penalized likelihood estimation (mple) for denoising spect images was performed and compared with other denoising methods such as wavelets or butterworth filtration. platelet-based mple factorization as a multiscale decomposition approach has been already proposed for better edges and surfaces representation due to poisson n...

UNLABELLED Probabilistic atlases are more representative of the population than single brain atlases. They allow anatomic and functional labeling of the results of group studies in stereotactic space and, hence, the automated anatomic labeling of individual brain imaging data. METHODS In the current study, probabilistic maps of the blood flow distribution of the middle cerebral artery (MCA) w...

Multimodality visualization aims at efficiently presenting integrated information obtained from different modalities, usually combining a functional modality (SPECT, PET, fMRI) with an anatomical modality (CT, MRI). This chapter presents a technique for 3D integrated visualization of SPECT and MR brain images, where MRI is used as a framework of reference for the display of the SPECT data. Meth...

Brain perfusion SPECT is a functional neuroimaging technique that allows noninvasive study of physiologic and physiopathologic events in the human brain. With the appropriate technique and careful interpretation of the information provided, brain perfusion SPECT has proven potential for patient management. SPECT has clinical value in the diagnosis, therapeutic management, and follow-up of patie...

Introduction: In this study the evaluation of a Platelet-based Maximum Penalized Likelihood Estimation (MPLE) for denoising SPECT images was performed and compared with other denoising methods such as Wavelets or Butterworth filtration. Platelet-based MPLE factorization as a multiscale decomposition approach has been already proposed for better edges and surfaces representation due to Poi...

Although extraosseous accumulations of 99mTc phosphate complexes are phenomena which can often be seen, no case showing extraosseous accumulation to brain tumor on SPECT has been reported. We report here two cases of primary brain tumor showing extraosseous accumulation of 99mTc phosphate in bone SPECT. 201Tl SPECT also showed increased 201Tl uptake by the tumor. Comparing bone SPECT with 201Tl...

Brain perfusion SPECT is a functional neuroimaging technique that allows noninvasive study of physiologic and physiopathologic events in the human brain. With the appropriate technique and careful interpretation of the information provided, brain perfusion SPECT has proven potential for patient management. SPECT has clinical value in the diagnosis, therapeutic management, and follow-up of patie...

BACKGROUND Partial volume effects in atrophied areas should be taken into account when interpreting brain perfusion single photon emission computed tomography (SPECT) images of neurodegenerative diseases. To evaluate both perfusion and atrophy using brain SPECT alone, we developed a new technique applying tensor-based morphometry (TBM) to SPECT. METHODS After linear spatial normalization of b...

Background. The presence of a noise component on 3D images single-photon emission computed tomo­graphy (SPECT) brain significantly distorts the probability distribution function (PD) radioactive count rate in images. and further filtering data, based subjective assessment image quality, have significant impact calculation volumetric cerebral blood flow values uptake asymmetry radiopharmaceutica...

Periodic lateralized epileptiform discharges (PLEDs), which are known as unusual electroencephalogram (EEG) patterns, are described in a patient who had stroke and seizures. This patient underwent Tc-99m HMPAO (hexamethyl propylene amine oxime) brain single photon emission computed tomography (SPECT) imaging both during PLEDs on EEG and after the cessation of PLEDs. The initial SPECT study reve...