Cancer initiation and progression is a challenging scenario through developmental processes, which may be more complicated by occurrence of metastasis. Basically, diverse genetic alterations, including mutations, formation of truncated proteins and related pathways play key roles either in diagnosis or the most influential therapeutic purposes. ...

Background: Palliative whole brain radiotherapy (WBRT) has been the standard treatment for brain metastases. Ionizing radiation is known to be one of the most potent cataractogenic agents. We aimed to evaluate two different radiotherapy techniques with respect to the doses received by the organs at risk (OAR) in patients with brain metastasis who undergone WBRT. Materials and Methods: Ten conse...

Medical Image segmentation is to partition the image into a set of regions that are visually obvious and consistent with respect to some properties such as gray level, texture or color. Brain tumor classification is an imperative and difficult task in cancer radiotherapy. The objective of this research is to examine the use of pattern classification methods for distinguishing different types of...

 Carcinosarcoma is a rare type of cancer that is composed of a mixture of sarcomatous and carcinomatous elements. Pulmonary carcinosarcoma has a 25% five-year survival rate with a prognosis poorer than other non-small cell lung carcinomas. Herein, we report a case of pulmonary carcinosarcoma and its 18F-FDG PET/CT findings. A 61-year-old male patient presented with brain symptoms, including hea...

In this study, prognostic factors in non small cell lung cancer (NSCLC) patients with brain metastasis, and relation between brain metastasis location and survival were investigated. 103 NSCLC patients with brain metastasis were enrolled in this study. Demographic, clinical characteristics and treatment modalities of the patients who were followed up in medical oncology department between May 2...

with poor prognosis, rapid growth, distant metastasis, early regional metastasis, and a high rate of recurrence. The parotid gland is the most common site of involvement, and the lungs and the bones are the most common sites of distant metastasis of SDC. Herein, we present a case of SDC of the parotid gland in a 62-year-old male patient with an unusual metastasis to the skin of the primary site...

OBJECTIVE  To determine the characteristics and prognosis of brain metastasised HER-2 positive breast cancer (BC) patients. STUDY DESIGN Descriptive study. PLACE AND DURATION OF Ankara Oncology Training Research Hospital, Turkey between 2000 2019. METHODOLOGY BC patients were analysed retrospectively 105 included in Age 18 years over, BC, with BM (brain metastases) inclusion criteria. Patients ...

adenoid cystic carcinoma (adcc) is a malignant neoplasm, which accounts for 5-10% of all salivary gland tumors (1). about 50% of these tumors originate from intraoral minor salivary glands usually in the hard palate (1). three clinically obvious characteristics of adcc include slow growth rate, perineural invasion and high incidence of distant metastasis (1). the most commonly-affected sites of...