Bovine respiratory disease (BRD) is the leading cause of morbidity and mortality in feedlot cattle. herpesvirus-1 (BHV-1) one main culprits BRD; however, research on BHV-1 hampered by lack suitable models for infection drug testing. In this study, we established a novel bovine tracheal organoid culture grown basement membrane extract type 2 (BME2) matrix compared it with air–liquid interface (A...

Primary infection by herpes simplex virus type 1 (HSV-1) can cause clinical symptoms in the peripheral and central nervous system, upper respiratory tract, and gastrointestinal tract. Recurrent ocular shedding leads to corneal scarring that can progress to vision loss. Consequently, HSV-1 is the leading cause of corneal blindness due to an infectious agent. Bovine herpesvirus 1 (BHV-1) has simi...

Bovine herpesvirus type-1 (BoHV-1) is a DNA virus that is classified in the family Herpesviridae, subfamily Alphaherpesvirinae and genus Varicellovirus. This virus causes the respiratory disease, abortion, conjunctivitis, infectious pustular vulvovaginitis or balanoposthitis and other clinical forms of the complex diseases. The aim of this study was to evaluate the seroprevalence and ri...

Herpesviruses have mainly co-evolved with their hosts for millions of years. Consequently, different related host species may have been infected by various genetically related herpesviruses. Illustrating this concept, several ruminant alphaherpesviruses have been shown to form a cluster of viruses closely related to bovine herpesvirus 1 (BoHV-1): namely bovine herpesvirus 5, bubaline herpesviru...