OBJECTIVE Injection of botulinum toxin into the anal sphincter is a novel and safe new treatment of chronic idiopathic constipation and anal fissure in children. The purpose of this study was to determine the utility of intra sphincteric injection of botox in the treatment of children with refractory constipation. METHODS All children who suffered from chronic constipation for more than three...

BACKGROUND The manipulations, casts, and Botox(®) method for treating idiopathic clubfoot is an alternative non-surgical treatment method. Botox(®)-induced reversible muscle paralysis of the gastrocsoleus enables a physician to manipulate and cast the clubfoot in greater dorsiflexion. Ultrasound is incorporated during the early treatment stages to monitor the underlying physiology of the muscle...

OBJECTIVE To examine pain relief in patients with neurogenic thoracic outlet syndrome (NTOS) after a single, low dose injection of botulinum toxin A (Botox) into the anterior scalene muscle (ASM) under computed tomographic (CT) guidance. DESIGN Prospective longitudinal study. SETTING Academic medical institution. PATIENTS Patients 18 years of age and older were evaluated for potential sca...

BACKGROUND Botulinum toxin (BTX) is an effective treatment for primary axillary hyperhidrosis. In this study we used two toxins not bioequivalent: BOTOX (Allergan, Inc.) and Dysport (Beaufour Ipsen Biotech). OBJECTIVE The objective was to compare the efficacy, safety, and tolerability of BOTOX and Dysport in the treatment of primary axillary hyperhidrosis using a conversion factor of 1:3, res...

PURPOSE To compare the efficacies and safeties of Meditoxin (Medy-Tox, Korea) and Botox in the treatment of essential blepharospasm. METHODS We performed a double-blind, randomized, comparative trial comparing Meditoxin and Botox for treatment of blepharospasm in 60 patients from the intention-to-treat (ITT) population and 52 patients from the per-protocol (PP) population. We analyzed the imp...

OBJECTIVES/HYPOTHESIS Centers for Disease Control and Prevention guidelines maintain that single-use vials cannot be used for multiple patients. Botox product labeling states that the reconstituted toxin should be used within 4 hours on a single patient based on concerns of reduced potency, contamination, and consequent infections. The purpose of this study was to determine the safety and effic...

The role of Botox in Brachial Plexus Birth Palsy (BPBP) is still evolving. It is mainly used to overcome the co-contractions commonly seen in patients with recovering BPBP. Co-contractions result from cross innervation and are the main reason for development of various deformities in birth palsy patients. Unwanted muscular co-contractions or inappropriate activation of anatagonist muslces can h...

BACKGROUND Chronic migraine (CM) is a neurological disorder associated with substantial disability. Botulinum toxin type A (Botox) is an approved and effective preventive treatment option for adult patients with CM. Transcranial magnetic stimulation (TMS) is an alternative treatment device delivering a brief pre-set magnetic pulse used for self-administration by the patient at home. Despite bei...

BACKGROUND Botox has been used primarily for treating rhytids of the upper face. Its use in the lower part of the face has been reported by several authors but there is a relative scarcity of information regarding the use of Botox in the chin and even fewer well-controlled studies in this area. This study reports the findings from a placebo-controlled trial of Botox for the treatment of chin rh...