نتایج جستجو برای: bone morphogenetic protein

تعداد نتایج: 1505298  

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2013

Journal: :Clinical Orthopaedics and Related Research® 2009

Journal: :The Journal of bone and joint surgery. British volume 2008
T W Axelrad B Steen D W Lowenberg W R Creevy T A Einhorn

Heterotopic ossification occurring after the use of commercially available bone morphogenetic proteins has not been widely reported. We describe four cases of heterotopic ossification in patients treated with either recombinant bone morphogenetic protein 2 or recombinant bone morphogenetic protein 7. We found that while some patients were asymptomatic, heterotopic ossification which had occurre...

Journal: :The New England journal of medicine 1996
A B Shafritz E M Shore F H Gannon M A Zasloff R Taub M Muenke F S Kaplan

BACKGROUND Fibrodysplasia ossificans progressiva is a heritable disorder of connective tissue characterized by congenital malformation of the great toes and postnatal formation of ectopic bone. Although the disorder was first described more than 300 years ago, the genetic defect and pathophysiology remain unknown. Bone morphogenetic proteins are potent bone-inducing morphogens that participate ...

Journal: :Journal of Hard Tissue Biology 2022

Bone morphogenetic protein (BMP) is the only cytokine that induces heterotopic new bone. BMP has been classified as a subfamily of TGF superfamily. The most important and essential aspect for clinical application replenishment reinforcement bone defects fragile areas with However, it difficult to ascertain long term results. In this study, we examined osteogenic potential in mouse femoral fasci...

Journal: :Proceedings of the National Academy of Sciences 1990

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