We examined the effects of chicken egg hydrolysate (also known as "bone peptide" or BP) on bone metabolism in 5- to 8-month-old orchidectomized dogs. The bone formation marker serum bone alkaline phosphatase (BAP) and the bone resorption marker urine deoxypyridinoline (DPD) were used as indicators to measure changes in bone metabolism. The following results were observed that Serum BAP was high...

Analyzing biochemical turnover markers will be helpful to predict the bone health status of individuals. The present study aimed at studying the two essential enzymes involved in bone turnover process viz., serum acid phosphatase and serum alkaline phosphatase which are considered as bone resorption and bone formation marker respectively among urban women aged 35 to 74 years. The findings well ...

Currently, imaging techniques are the leading methods used to diagnose of metastasis to bone. However, these techniques are expensive, expose patients to toxic and radioactive compounds, and monitor response to treatment poorly; these drawbacks have prompted the search for alternative screening methods. Therefore, bone metabolic markers have been evaluated as possible methods to diagnose and mo...

Our goal is to evaluate skeletal anabolic response to mechanical loading in different age groups of C57B1/6J (B6) and C3H/HeJ (C3H) mice with variable loads using bone size, bone mineral density (BMD), and gene expression changes as end points. Loads of 6-9 N were applied at 2 Hz for 36 cycles for 12 days on the tibia of 10-wk-old female B6 and C3H mice. Effects of a 9-N load on 10-, 16-, and 3...

BACKGROUND Advanced oxidation protein products (AOPPs) are acknowledged as a novel marker of oxidation-mediated protein damage. This study aimed to investigate the plasma levels of AOPPs in postmenopausal osteoporotic women, and to determine the relationship between AOPPs accumulation and lumbar bone mineral destiny (BMD) or bone turnover markers. MATERIAL AND METHODS Lumbar BMD was measured ...

The pathogenesis of osteoarthritis (OA) includes complex events in the whole joint. Cartilage loss and bone remodelling are central in OA progression. In this project, we investigated the feasibility of quantifying OA by analysis of the tibial trabecular bone structure in low-field knee magnetic resonance imaging (MRI). The development of automatic and more sensitive indicators of OA in conjunc...